Search Results for: hypogranulosis

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…enable differentiation of authentic lichen planus from simulators of it induced by a drug, e.g., focal parakeratosis, focal hypogranulosis, many individual necrotic keratocytes (some of them in clusters), and the presence of eosinophils; each…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus-like keratosis

…idermis Jagged acanthosis sometimes in association with foci in which the epidermis is thin Hypergranulosis in some foci and hypogranulosis in others Ortho- and parakeratosis to variable extent Residual solar lentigo obscured partially by…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…in which hypergranulosis is covered by orthokeratosis arrayed in a basket-weave pattern. Figure 3.19 A. Hypergranulosis. B. Hypogranulosis. HYPERKERATOSIS [Gk. hyper (above) + keratos (horn) + –osis (condition)]: A thickened cornified layer…

Histologic Diagnosis of Inflammatory Skin Diseases

Pityriasis rubra pilaris

…the viable epidermis Few mitotic figures present above the epidermal basal layer Granular layer mostly preserved, but slight hypogranulosis in foci Alternation of orthokeratosis and parakeratosis in a pattern that resembles vaguely a checkerboard…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Follicular Degeneration Syndrome?

…re, the epidermis was said by them to become altered and to display thin, elongated rete ridges, thin suprapapillary plates, hypogranulosis, and a normal cornified layer. LoPresti et al. believed that a burn by the hot petrolatum was responsible for…

Histologic Diagnosis of Inflammatory Skin Diseases

Psoriasis

…ytes in discrete foci in the lower part of the epidermis Spongiform and subcorneal pustules in the epidermis of some lesions Hypogranulosis in some foci Mounds of parakeratosis with neutrophils at their summit staggered in the stratum corneum,…

Differential Diagnosis in Dermatopathology

Discussions

…in which there may be eosinophils in the dermal infiltrate, many necrotic keratocytes in a focally thinned epidermis, focal hypogranulosis, and parakeratosis Lichenoid discoid lupus erythematosus in which the epidermal basement membrane often is…

Differential Diagnosis in Dermatopathology

Discussions

…eratosis overlie an epidermis that, at the least, is thickened focally. In loci, there may be zones of epidermal atrophy and hypogranulosis. The epidermis assumes a pink cast as a consequence of premature cornification of keratocytes, which often is…