Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

Lichen planus Synonyms Lichen ruber planus Lichen ruber Presentation stereotypical Age and sex More common in women, especially young and middle-aged adults Distribution of lesions Flexor surface of forearms and wrists, but no site is exempt. Occu…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus-like keratosis

Lichen planus-like keratosis Presentation stereotypical Age and sex Older individuals bombarded by rays of the sun for many years Distribution of lesions Sun-exposed sites, especially the chest and shoulders Configuration of lesions Round Individual…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Histologic Diagnosis of Inflammatory Skin Diseases

Pityriasis rubra pilaris

Pityriasis rubra pilaris Synonyms Pityriasis pilaris Presentation stereotypical Age and sex Adults in about the fifth decade of life and children in the first 5 years of life; same frequency in both sexes Distribution of lesions Symmetric and widesp…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Follicular Degeneration Syndrome?

“An irreversible alopecia of the scalp occurs in negro women who straighten their hair with hot combs. The disease is common and distinctive, clinically and histopathologically. . . . Hot petrolatum used with the comb causes a chronic inflamm…

Histologic Diagnosis of Inflammatory Skin Diseases

Psoriasis

Psoriasis Presentation stereotypical Age and sex Persons of any age and of both sexes Distribution of lesions Localized, e.g., single papule or plaque, or universal, i.e., erythroderma; between these extremes, a preference for elbows and knees, scal…

Differential Diagnosis in Dermatopathology

Discussions

Lichen planus-like keratosis may be confused easily with lichen planus histopathologically, especially in sections from a specimen taken by punch technique. Ostensibly, both are superficial perivascular dermatitides with lichenoid infiltrates made u…

Differential Diagnosis in Dermatopathology

Discussions

Distinction histopathologic between lichen planus-like keratosis and most solar keratosis is not difficult in some instances. When, however, a solar keratosis is accompanied by lichenoid infiltrates of lymphocytes, it may have many attributes in com…