Therapeutic Strategies in Dermatology

Ichthyoses/Disorders of Cornification: Overview

Overview Ichthyosis results from abnormal retention and/or production of the stratum corneum layer of the epidermis. Acquired ichthyosis can be a cutaneous manifestation of an underlying disease (e.g., malignant neoplasm, metabolic disorder, malabso…

A Clinical Atlas of 101 Common Skin Diseases

Ichthyoses

…ons, namely, ichthyosis vulgaris (and its look-alike, acquired ichthyosis), X-linked ichthyosis, and lamellar ichthyosis. Other conditions purported to be ichthyosis, among them nonbullous congenital ichthyosiform erythroderma, ichthyosis hystrix, an…

A Clinical Atlas of 101 Common Skin Diseases

Epidermal Nevi

Epidermal nevi are hamartomas in which the epidermis is abnormal, being hyperkeratotic, and in which lesions are aligned along Blaschko’s lines….

Differential Diagnosis in Dermatopathology

Ichthyosis vulgaris vs. X-linked ichthyosis

Epidermal nevi are hamartomas in which the epidermis is abnormal, being hyperkeratotic, and in which lesions are aligned along Blaschko’s lines….

Therapeutic Strategies in Dermatology

Palmar and Plantar Keratoderma: Overview

Overview Palmoplantar keratodermas (PPK) can occur as a primary, inherited disorder of the volar surfaces, or as part of a generalized disorder, such as psoriasis, cutaneous T-cell lymphoma, or ichthyosis. Discussion of treatment here is limited to…

A Clinical Atlas of 101 Common Skin Diseases

Palmar and Plantar Keratoderma

A keratotic condition of the palms and soles, inherited usually, but sometimes acquired, in which involvement may be diffuse, circumscribed (including striate), or punctate….

A Clinical Atlas of 101 Common Skin Diseases

Darier’s Disease

A genetically determined disorder in which numerous closely set keratotic papules are present on the skin, especially the trunk, in nail units, and on mucous membranes, particularly the palate, but also rarely in other parts of the gastrointestinal…

A Clinical Atlas of 101 Common Skin Diseases

Sarcoidosis

An inflammatory (granulomatous) process that involves, among other organs, the lungs, lymph nodes, and skin, and the latter in the form usually of papules, sometimes in arcuate and annular configuration, especially on a face, but also on the extremi…

A Clinical Atlas of 101 Common Skin Diseases

Keratosis Pilaris/Lichen Spinulosus

Keratotic spikes that emerge from dilated ostia of infundibula and are equidistant from one another. The term keratosis pilaris refers to the phenomenon when it presents itself without any distinct arrangement of individual lesions, whereas the desi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Ichthyoses?

…mmatory cells. Darier included among the ichthyoses xeroderma, ichthyosis nitida, ichthyosis nigricans, ichthyosis serpentine, ichthyosis sauriasis, and ichthyosis hystrix, the latter two conditions combined by him under the name “ichthyosis co…