Search Results for: infiltrate

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Therapeutic Strategies in Dermatology

Lupus: Key Points

…confirmed by skin biopsy, which in general reveals a vacuolar interface dermatitis, often in association with a lymphocytic infiltrate with plasma cells, epidermal atrophy, and mucin. Variants exist, such as bullous lupus, which is marked by the…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…ll of venules and with extravasated erythrocytes = Leukocytoclastic vasculitis     Perivascular Lympho-plasmacytic Infiltrates Infiltrates of lymphocytes and plasma cells around venules, usually of both vascular plexuses. Click image to…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…cell + 10.5.31B: Lymphocytes and numerous eosinophils = Response to an assault by an arthropod The moderately dense and deep infiltrate is most consonant with a reaction to the “bite” of a tick. Note also the hint of a wedge shape formed…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…y basket-weave, but compact orthokeratosis especially above foci of hypergranulosis Fully developed Superficial perivascular infiltrate of lymphocytes Bandlike infiltrate of lymphocytes across the upper part of the dermis, obscuring the…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ulosis, that lymphoma being confirmed at higher magnification by notation of numerous atypical lymphocytes in the mixed-cell infiltrate. Only two other diseases are characterized by infiltrates in the shape of a wedge, namely, the inflammatory…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…a. When it is largely noncellular, an infiltrate may consist, for example, of mucin, amyloid, colloid, or urate. Noncellular infiltrates are referred to as deposits. An infiltrate made up of a single type of cell is considered to be monomorphous…

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