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A Clinical Atlas of 101 Common Skin Diseases

Lymphomatoid Papulosis

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A distinctive type of CD 30 lymphoma characterized by the presence mostly of papules, some of them purpuric, that may ulcerate and heal with a scar, and by lesions that tend to come and go for years, eventually disappearing entirely or, on occasion, becoming nodular and even tumorous, which is an indication of likelihood of detectable lymphomatous involvement of some organs besides the skin.

Therapeutic Strategies in Dermatology

Lymphomatoid Papulosis: Overview

Overview Lymphomatoid papulosis (LyP) is an inflammatory disorder affecting primarily the upper dermal blood vessels. It is characterized by the presence of CD30-positive lymphocytes (sometimes large and atypical) in the dermal infiltrate. Individua…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomas (Other Than Mycosis Fungoides and Lymphomatoid Papulosis)

…usters on any anatomic site. When “primary,” B-cell lymphomas of the skin seem to be wholly cutaneous with no evidence of extracutaneous manifestations after complete staging has been performed. The major categories of primary cutaneous B-c…

Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides: Overview

Overview Therapy of cutaneous T-cell lymphoma often requires specialized knowledge, and for this reason it is often appropriate to refer such patients to a medical center with specialized knowledge in the management of CTCL. Since early aggressive t…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris: Overview

…emphigus is associated with an underlying malignancy (usually lymphoma) or with Castleman’s disease (especially in children). It is very refractory to treatment. Treatment algorithms are similar to the treatment of pemphigus vulgaris, with the…

Therapeutic Strategies in Dermatology

Photosensitivity Dermatoses: Overview

…o demonstrate histologic features resembling cutaneous T cell lymphoma (so called actinic reticuloid). Currently, this end-stage condition is termed chronic actinic dermatitis, and includes the conditions previously labeled photosensitive eczema, act…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomatoid Papulosis

A distinctive type of CD 30 lymphoma characterized by the presence mostly of papules, some of them purpuric, that may ulcerate and heal with a scar, and by lesions that tend to come and go for years, eventually disappearing entirely or, on occasion,…

A Clinical Atlas of 101 Common Skin Diseases

Mycosis Fungoides

A systemic lymphoma of T-lymphocytes that manifests itself first in the skin as macules and then patches that often are scaly. Most people with the disease have only scaly macules and patches for a lifetime, but some patients may develop papules, pl…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Treatment

…ith dermatitis herpetiformis are at increased risk to develop lymphoma of the GI tract. A gluten-free diet reduces the risk of this complication. Treatment with dapsone alone (without gluten avoidance) does not reduce the risk of lymphoma. Patients w…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Key Points

…y hypothyroidism, as well as an increased risk of non-Hodgkin lymphoma, specifically bowel-associated T cell lymphoma. Dental enamel defects are found in almost half of DH patients, similar to but milder than those described for celiac disease. Patie…

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