1 2 3 10
A Clinical Atlas of 101 Common Skin Diseases

Darier’s Disease

  • at015g01.jpg
  • at015g02.jpg
  • at015g03a.jpg
  • at015g03b.jpg
  • at015g04.jpg
  • at015g05.jpg
  • at015g06.jpg
  • at015g07.jpg
  • at015g08.jpg
  • at015g09.jpg

A genetically determined disorder in which numerous closely set keratotic papules are present on the skin, especially the trunk, in nail units, and on mucous membranes, particularly the palate, but also rarely in other parts of the gastrointestinal tract.

A Clinical Atlas of 101 Common Skin Diseases

Darier’s Disease

A genetically determined disorder in which numerous closely set keratotic papules are present on the skin, especially the trunk, in nail units, and on mucous membranes, particularly the palate, but also rarely in other parts of the gastrointestinal…

Therapeutic Strategies in Dermatology

Darier’s Disease

A genetically determined disorder in which numerous closely set keratotic papules are present on the skin, especially the trunk, in nail units, and on mucous membranes, particularly the palate, but also rarely in other parts of the gastrointestinal…

Therapeutic Strategies in Dermatology

Darier’s Disease: Treatment

Treatment First-line therapy: The first-line therapy for Darier’s disease is systemic retinoids. First steps The currently accepted primary treatment of moderate-to-severe Darier’s disease is systemic retinoids. Isotretinoin and acitretin are equal…

Therapeutic Strategies in Dermatology

Darier’s Disease: Key Points

…ilant monitoring for superinfection is critical. Introduction Darier’s disease is a genodermatosis of autosomal dominant inheritance causing abnormalities of keratinization. The gene mutation associated with Darier’s is the ATP2A2 gene encoding SERC…

Therapeutic Strategies in Dermatology

Darier’s Disease: References

…oue C, Yokoyama Y, Ishikawa O. (2011). Successful treatment of Darier’s disease with adapalene gel, Ped Derm, 28:197-198. Frezzini C, Cedro M, Leao JC, Porter S. (2006). Darier disease affecting the gingival and oral mucosal surfaces, Oral Surg Oral…

Therapeutic Strategies in Dermatology

Darier’s Disease: Clinical Case

…nical Case Case 1 32-year-old male Presents with worsening Darier’s disease No significant past medical history except for known diagnosis of Darier’s. The patient was intermittently on oral isotretinoin, which controlled his disease during times…

A Clinical Atlas of 101 Common Skin Diseases

Epidermal Nevi

Epidermal nevi are hamartomas in which the epidermis is abnormal, being hyperkeratotic, and in which lesions are aligned along Blaschko’s lines….

Therapeutic Strategies in Dermatology

Urticaria Pigmentosa / Mastocytosis: Key Points

Key Points Mastocytosis can occur at any age, and may involve the skin, or affect internal organs including the bone marrow and liver/spleen/lymphatic tissues Urticaria pigmentosa is a form of cutaneous mastocytosis most common in childhood, char…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Overview

Overview Hailey-Hailey disease (HHD), also called benign familial pemphigus, is an autosomal-dominant disorder characterized by a defect in keratinocyte adhesion. HHD most frequently involves intertriginous areas, where exacerbations are triggered b…

Therapeutic Strategies in Dermatology

Candidiasis: Key Points

Key Points Candidiasis typically affects mucosal sites and moist and/or occluded areas of skin: groin, axilla, inframammary, infra-abdominal pannus, glans penis (in uncircumcised males), and orogenital mucosal sites. Predisposing factors include o…

1 2 3 10