Therapeutic Strategies in Dermatology

Chondrodermatitis Nodularis Helicis: Key Points

Key Points Chondrodermatitis nodularis helicis (CNH) is an uncommon, strikingly painful lesion on the helix or antihelix of the ear, which often appears as a crusted ulceration mimicking a cutaneous malignancy. Diagnosis may be made by clinical exa…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Origin of Adnexal Neoplasms?

…s, such as trichoblastoma, sebaceoma, hidradenoma clear-cell, leiomyoma, neuroma, or hemangioma, remains recondite. In most instances, those proliferations are not continuous with epidermis (surface or infundibular) or with preexisting epithelial or…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Study By Disease

…hen simplex chronicus of an oral mucous membrane) (Quiz #852) Leiomyoma (Quiz #114) Leiomyoma, hair erector type (Quiz #633) Leiomyosarcoma (Quiz #625) Lepromatous leprosy (Virchowian hanseniasis) (Quiz #826) Lepromatous leprosy (Virchowian hansenias…

Dermatology Practical & Conceptual

Glomangiosarcoma in the shoulder of a 51-year-old man

…inology. For example, we do not call leiomyosarcoma malignant leiomyoma or angiosarcoma malignant hemangioma. Glomangiosarcoma is very rare. The first case was reported by Lumley and Stansfeld in 1972, who used the term of malignant glomus tumor to d…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Metastasizing Dermatofibroma?

…s with rare metastasis which include such examples as uterine leiomyomas and salivary mixed tumor.” Colome-Grimmer MI, Evans HL. Metastasizing cellular dermatofibroma: a report of two cases. Am J Surg Pathol 1996;20:1361–67. “Low-…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nuclear Atypia, Cytoplasmic Atypia, and Architectural Atypia?

…es, as in leiomyosarcoma, in contrast to absence of them from leiomyoma. It cannot be denied, though, that in most instances, striking pleomorphism of nuclei signifies malignant neoplasia, even if not synonymous with it. In sum, there are no-agreed o…

Dermatology Practical & Conceptual

Dermoscopic findings in a patient with multiple piloleiomyomas

Abstract Piloleiomyoma can manifest itself as a pigmented lesion and part of the differential diagnosis with other pigmented skin lesions. However, we are not aware of previous descriptions in the literature of the dermoscopic features of piloleiomy…