Search Results for: leukocytoclasis

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…nuclear “dust” of lymphocytes that has been ingested by macrophages. In short, if the meaning of the word “leukocytoclasis” is to be understood clearly, it must be modified always by “of neutrophils” or “of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Subcorneal Pustular Dermatosis?

…psoriasis (von Zumbusch type) may sometimes present differential diagnostic difficulties. Systemic symptoms (fever, malaise, leukocytoclasis), the presence of spongiform pustules within the epidermis, and the failure of pustular psoriasis to respond…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Urticarial Vasculitis?

…rivascular and interstitial infiltrate composed mostly of neutrophils and residua of them, i.e., nuclear “dust” (leukocytoclasis). Nearly always, erythrocytes are extravasated among the inflammatory cells. Fibrin, however, is not present…

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous Fat: Panniculitis

…t with tuberculosis, it is given the name erythema induratum. Small-vessel vasculitis in the subcutaneous fat accompanied by leukocytoclasis of neutrophils, no matter how minute the amount of nuclear “dust,” is leukocytoclastic…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…in in the wall of venules, in the context of this infiltrate of inflammatory cells, makes this a vasculitis; the presence of leukocytoclasis makes it leukocytoclastic vasculitis. 10.58.20A: Vasculitis, small-vessel, neutrophilic + 10.58.20B:…

Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

…infarction secondary to occlusion by thrombi in the lumen and fibrin in the wall of venules. Urtica never is associated with leukocytoclasis of neutrophils. Clue to specific diagnosis histopathologic Nuclear “dust” of neutrophils in the…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…structures epidermal and adnexal epithelial. Necrosis of neutrophils also occurs in leukocytoclastic vasculitis, as the term leukocytoclasis (nuclear “dust,” in this instance of neutrophils) denotes. Neutrophils die as part of a…