Histologic Diagnosis of Inflammatory Skin Diseases

Lipodystrophy

Lipodystrophy Synonyms Lipoatrophy Wucher atrophy Presentation stereotypical Age and sex Females, first decade of life Distribution of lesions Upper half of body in the “partial” expression of the process and widespread in the “t…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…he two vesicular diseases are unrelated to one another. Error: Lipodystrophy refers to a specific disease. Reason: Lipodystrophy is to subcutaneous fat what anetoderma is to the dermis, namely, loss of tissue, in the instance of lipodystrophy of adip…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophoderma?

“Atrophoderma, or atrophia cutis. Atrophy of the skin may be quantitative or qualitative; idiopathic or symptomatic; diffused or circumscribed. Crocker gives this useful table: Pigmentosum Juvenilis Albidum Diffusum Senilis…

Histologic Diagnosis of Inflammatory Skin Diseases

a-1 antitrypsin deficiency

α-1 antitrypsin deficiency Presentation stereotypical Age and sex Any age, predominantly women Distribution of lesions Particularly on the trunk and extremities Configuration of lesions Shapes of subcutaneous nodules bizarre, ulceration with dischar…

Histologic Diagnosis of Inflammatory Skin Diseases

Introduction

The understanding of diseases has been founded traditionally on the tripod of diagnosis (what is it?), etiology (what caused it?), and pathogenesis (how did it happen?). Current emphasis in medicine, however, is on the latter two legs of that stand,…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Differential Diagnosis in Dermatopathology

Discussions

Atrophic lichen planus and atrophic discoid lupus erythematosus pose problems in differential diagnosis histopathologic because they have several findings in common, among them compact orthokeratosis, focal hypergranulosis, epidermis thinned and ass…

Histologic Diagnosis of Inflammatory Skin Diseases

Post-inflammatory pigmentary alteration

Post-inflammatory pigmentary alteration Synonyms Postinflammatory pigmentary change Presentation stereotypical Age and sex No preference for age or sex, more prominent in dark-skinned individuals Distribution of lesions Sites of a previous dermatiti…