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A Clinical Atlas of 101 Common Skin Diseases

Lupus Erythematosus

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An inflammatory process that expresses itself in the skin in protean ways that are variations on a basic pathologic theme, and includes evanescent patches on the face (“butterfly blush”), scaly papules and plaques that resolve with atrophy and hyperpigmentation (classic discoid lupus erythematosus), arcuate, annular, and serpiginous lesions (subacute cutaneous lupus erythematosus), nonscaling plaques (tumid lupus erythematosus), subcutaneous nodules (lupus profundus), and blisters (bullous lupus erythematosus).

A Clinical Atlas of 101 Common Skin Diseases

Lupus Erythematosus

…at resolve with atrophy and hyperpigmentation (classic discoid lupus erythematosus), arcuate, annular, and serpiginous lesions (subacute cutaneous lupus erythematosus), nonscaling plaques (tumid lupus erythematosus), subcutaneous nodules (lupus profu…

Therapeutic Strategies in Dermatology

Lupus

…at resolve with atrophy and hyperpigmentation (classic discoid lupus erythematosus), arcuate, annular, and serpiginous lesions (subacute cutaneous lupus erythematosus), nonscaling plaques (tumid lupus erythematosus), subcutaneous nodules (lupus profu…

Therapeutic Strategies in Dermatology

Lupus: Key Points

…disease, only the management of more common forms of cutaneous lupus will be discussed here. The four forms of cutaneous lupus discussed are: discoid lupus, subacute cutaneous lupus, lupus profundus, and bullous lupus. Subcutaneous lupus may be drug-…

Therapeutic Strategies in Dermatology

Lupus: Treatment

…nsitivity syndrome. Cosmetic surgical correction of lesions of lupus profundus, even when inactive, may be associated with exacerbation of disease and should be undertaken with caution. When to refer to a dermatologist If the diagnosis of lupus is…

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Key Points

…ay be an indication of a multisystem disease such as chilblain lupus erythematosus, a rare variant of systemic lupus Introduction Chilblains, also termed pernio, is a benign inflammatory condition of the distal skin which occurs in cold, damp enviro…

Therapeutic Strategies in Dermatology

Lupus: Initial Evaluation

Initial Evaluation Discoid lupus erythematosus Subacute lupus erythematosus Systemic lupus erythematosus Neonatal lupus erythematosus Lupus profundus Differential diagnosis Rosacea, face Ti…

Therapeutic Strategies in Dermatology

Lupus: Clinical Cases

…rrent lesions on cheeks and scalp Negative workup for systemic lupus erythematosus (recent) Lesions are itchy, exacerbated by sun exposure No current treatment Initial evaluation Diagnosis: Discoid lupus (confirmed by biopsy) Desonide 0.05% ointmen…

Therapeutic Strategies in Dermatology

Lupus: References

…y of mycophenolate mofetil in antimalarial-resistant cutaneous lupus erythematosus, JAAD, Epub ahead of print. Kuhn A, Ruland V, Bonsmann G (2010) Cutaneous lupus erythematosus: Update of therapeutic options (part I and II), JAAD, Epub ahead of print…

A Clinical Atlas of 101 Common Skin Diseases

Alopecias

Loss of hair attributable either to the effects of inflammatory cells on follicles or to physiological or mechanical factors in which inflammatory cells play no role. Although the scalp is the site most often affected, any region of the skin that be…

Differential Diagnosis in Dermatopathology

Lupus profundus vs. Morphea profundus

Loss of hair attributable either to the effects of inflammatory cells on follicles or to physiological or mechanical factors in which inflammatory cells play no role. Although the scalp is the site most often affected, any region of the skin that be…

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