Search Results for: lymphatics

Therapeutic Strategies in Dermatology

Erysipelas/Cellulitis: Key Points

…of cases) but commonly has facial involvement (17%), is unilateral, sharply demarcated, typically involves more superficial lymphatics within the dermis to give a waxy or intensely superficial edematous (peaud’orange) appearance. Cellulitis…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphatics

…in the upper part of the reticular dermis, just beneath the superficial plexus of blood vessels. The structure of cutaneous lymphatics enables clearance from the dermis of fluids, macromolecules, cells, and foreign material. The twin roles of the…

A Clinical Atlas of 101 Common Skin Diseases

Melanoma

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate,…

A Clinical Atlas of 101 Common Skin Diseases

Deep Fungal Infections

Cutaneous and subcutaneous lesions, usually nodules, that have become keratotic, crusted, and ulcerated as a consequence of infection by a variety of deep fungi, i.e., fungi situated in the dermis and subcutis, some of which may be disseminated to…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphedema

…search for microfilariae of filariasis. Cause and mechanism Primary lymphedema is hereditary and is the result of defective lymphatics, i.e., hypoplastic vessels. Obstruction or infiltration of lymphatics leads to stasis of lymph, as in metastasis…

From the Dermatologikum Hamburg: Quiz

From the Dermatologikum Hamburg: Quiz

…d as a benign vascular tumor, but it has been a matter of controversy whether it can be differentiated from blood vessels or lymphatics and whether it is a true neoplasm or a malformation. Franke et al, in 2004, showed that endothelia of hobnail…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 11.12.1A: Fibrosing dermatitis + 11.12.1B: Widely dilated lymphatics in company with an increased number of thick-walled blood vessels lined by plump endothelial cells, those vessels in the upper part of the dermis being oriented mostly…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…for many years, whereas, others live for weeks only. T lymphocytes migrate from blood to tissues, travel to lymph nodes via lymphatics, from nodes into the thoracic duct, and, eventually, back into the bloodstream. T cells recirculate continuously…

Histologic Diagnosis of Inflammatory Skin Diseases

Erysipelas

…d mostly of neutrophils, but also of lymphocytes and, episodically, of eosinophils around venules Widely dilated venules and lymphatics in the upper part of the dermis Edema of the papillary dermis Fully developed Moderately dense infiltrate of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Satellite, in Transit, Regional, and Distant Metastases?

…ytic Disorders. London, England: Chapman & Hall Medical Publishers, 1992:314. “In-transit metastases appear in the lymphatics or soft tissues between the primary melanoma and the first major regional nodal basin as either subcutaneous or…