Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…alternatives of cryotherapy or intralesional vinca alkaloids. Lymphedema may precede or accompany KS. Control of the lymphedema with elevation and support stockings is important for patients with lower-extremity lesions. Ulceration and secondary inf…

Therapeutic Strategies in Dermatology

Erysipelas/Cellulitis: Key Points

Key Points Erysipelas and cellulitis are infections of the dermis and subcutaneous layers of the skin that are rapidly progressive and are often accompanied by systemic signs, such as fever, leukocytosis, and elevated markers of systemic inflammat…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphedema

Lymphedema Presentation stereotypical Age and sex Adults usually, women more than men Distribution of lesions Distal extremities, legs more than arms; genitalia episodically Arrangement of lesions Diffuse involvement of parts, e.g., elephantiasis In…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphedema

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…lated thick-walled venules perpendicular to the skin surface = Lymphedema, chronic ┬áThe changes of lymphedema present for many years are fundamentally those of a scar that eventually affects most or all of the dermis, as shown here. 11.12.3A: F…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…at a site of infection previous by zoster (Quiz #614) Chronic lymphedema (Quiz #518) Chronic lymphedema (Quiz #519) Chronic lymphedema secondary to rosacea (Quiz #419) Cicatricial pemphigoid (Quiz #876) Cicatricial pemphigoid (benign mucous membrane…

Dermatology Practical & Conceptual

Multiple confluent reddish nodules

The patient A 48-year-old fisherman from Amazonas (north of Brazil) developed a small papule on the anterior left leg after a traumatic injury with a piece of wood 20 years ago. Over the course of years, multiple large, confluent, reddish to brownis…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphatics

The skin is home to an elaborate network of lymphatic vessels that parallels the major blood vascular plexuses but is independent of them. From a superficial plexus of lymphatic capillaries arise progressively thicker-walled lymphatic vessels whose…

Dermatology Practical & Conceptual

A verrucous plaque on the lower leg

Quiz case A 52-year-old male patient from South Africa presented with a lesion on his lower left leg extending from the ankle to just below the knee that has been present for twenty years. The lesion first developed as a verrucous nodule close to th…

Histologic Diagnosis of Inflammatory Skin Diseases

Factitious dermatitis and panniculitis

Factitious dermatitis and panniculitis Synonyms Self-induced skin disease Pathomimicry Dermatitis artifacta Munchhausen syndrome Dermatitis passivata Factitial lymphedema (Secretan syndrome) Malingering Self-mutilation Presentation stereotypical Age…