Therapeutic Strategies in Dermatology

Superficial Fungal Infections: Therapy: Tinea versicolor

…versicolor Tinea versicolor is a superficial skin infection by Malassezia furfur (a.k.a. Pityrosporum ovale and Pityrosporum orbiculare). Epidemiology Tinea versicolor is a very common skin infection, affecting up to 2-8% individuals in the United St…

A Clinical Atlas of 101 Common Skin Diseases

Tinea Versicolor

An inflammatory disease caused by the fungus Malassezia furfur, the organisms of which proliferate in a slightly thickened stratum corneum. It manifests clinically as white or light brown macules that may be discrete or confluent, on the trunk espec…

Therapeutic Strategies in Dermatology

Seborrheic Dermatitis: Key Points

Key Points Seborrheic dermatitis is a chronic intermittent rash typically affecting the face, ears, scalp, and trunk. It is marked by an erythematous papular or macular eruption often with greasy yellow scale, sometimes accompanied by pruritus. Thi…

Therapeutic Strategies in Dermatology

Seborrheic Dermatitis: Principles of Seborrheic Dermatitis Management

Principles of Seborrheic Dermatitis Management Seborrheic dermatitis is a chronic intermittent condition. There is an initial treatment period followed by maintenance therapy. Many patients will relapse if maintenance therapy is not adequate. Topi…

Therapeutic Strategies in Dermatology

Seborrheic Dermatitis: Initial Evaluation

Initial Evaluation Erythematous, scaly, oily-looking patches on the face (nasolabial folds, medial cheeks, chin, glabella, forehead) and thick crust on the scalp are typical affected areas. Seborrheic dermatitis can also present…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…o be preserved. That circumstance enables hyphae and spores of Malassezia furfur to be spotted easily. 10.105.2A: Perivascular dermatitis, lymphocytic + 10.105.2B: Short hyphae and spores in the cornified layer whose outline is basket-weave…

Histologic Diagnosis of Inflammatory Skin Diseases

Tinea versicolor

…in keratocytes. Azelaic acid, a dicarboxylic acid produced by Malassezia furfur, seems to be responsible for the interference with the transfer of melanosomes to keratocytes. Another hypothesis is that Malassezia furfur produces a factor that protec…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dandruff a Disease?

…Forensic Sci 1998;43(4):901-2. “The yeasts of the genus Malassezia have been associated with a number of diseases affecting the human skin, such as pityriasis versicolor, Malassezia (Pityrosporum) folliculitis, seborrheic dermatitis and dandru…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…the infectious diseases tinea versicolor (caused by the fungus Malassezia furfur) and verruca plana (caused by a papillomavirus). Compact orthokeratosis [L. compactus (packed closely together)] designates orthokeratotic cells that are crowded and coh…