Search Results for: mast cells

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Therapeutic Strategies in Dermatology

Urticaria Pigmentosa / Mastocytosis: Key Points

mastocytosis may have a single isolated mastocytoma, diffuse cutaneous mastocytosis, urticaria pigmentosa, or a rare form of mast cells in the skin seen in adults characterized by telangiectasias and faint lesions, called telangiectasia macularis…

A Clinical Atlas of 101 Common Skin Diseases

Urticaria Pigmentosa

A benign neoplastic process of mast cells. In children the condition manifests itself as papules, nodules, and tumors that urticate upon rubbing, and as blisters; in adults it expresses itself as macules and papules accompanied by telangiectases…

Therapeutic Strategies in Dermatology

Urticaria: Initial Evaluation

…fungal, parasitic, viral), autoimmune disease (including production of auto-antibodies against the IgE receptor, triggering mast cell degranulation), or drug reaction. Whereas foods may be a relevant trigger for acute urticaria, the role of food…

Therapeutic Strategies in Dermatology

Urticaria Pigmentosa / Mastocytosis: Treatment

…emic symptoms, abnormal blood counts, or elevated tryptase levels warrant more thorough investigation for potential systemic mastocytosis. Patients with cutaneous or systemic mastocytosis may be at risk of anaphylaxis. Patients with high burdens of…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…ells” is understood as being generic for neutrophils, eosinophils, lymphocytes, plasma cells, and histiocytes; whether mast cells, basophils, Langerhans” cells, dermal dendrocytes, fibrocytes, and platelets should be considered…

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

…Purpose: To review the histologic differential diagnosis of conditions with epithelial and histiocytic multinucleated giant cells—since multinucleated giant cells in the epidermis are not always pathognomonic of a cutaneous herpes virus…

A Clinical Atlas of 101 Common Skin Diseases

Neurofibromatosis

…of melanocytes (e.g., axillary “freckles” and café au lait “spots”) and of proliferations of Schwann cells (e.g., papules, nodules, and tumors of neurofibroma). The cutaneous lesions may be accompanied by neoplasms with…

Therapeutic Strategies in Dermatology

Stings: Treatment

…th IgE- and non-IgE-mediated mechanisms and do not always represent true anaphylaxis. Non-IgE-mediated reactions may reflect mast cell dysfunction. Patients with known mastocytosis should be prescribed auto-injectable epinephrine (such as an…

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