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A Clinical Atlas of 101 Common Skin Diseases

Melanocytic Nevi and Melanotic Macules

…melanocytic nevi) of various specific types, all of which are composed of abnormal melanocytes and manifested clinically as lesions of different colors, shapes, and sizes, among them, macules and patches, papules and plaques, and nodules and tumors….

A Clinical Atlas of 101 Common Skin Diseases

Melanoma

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

A Clinical Atlas of 101 Common Skin Diseases

Vitiligo

An inflammatory process that is idiopathic and results in depigmentation of the skin consequent to loss of melanocytes from the epidermis, and in whitening of hair that follows loss of melanocytes from the bulb of follicles….

A Clinical Atlas of 101 Common Skin Diseases

Melasma

…macules and patches mostly in the middle third of the face, vertically and horizontally, distributed symmetrically and occurring mainly in postpubescent women as a consequence of the combined effects of estrogen and ultraviolet light on melanocytes….

Therapeutic Strategies in Dermatology

Facial Melanosis, Melasma: Key Points

…igment in the epidermis, dermis, or both; increased number of melanocytes or dermal melanophages in the dermis may also result in melasma. It usually appears in association with estrogen exposure in the form of oral contraceptive (OCP) use, hormone r…

Therapeutic Strategies in Dermatology

Melanoma: Key Points

…cted patients. Introduction Melanoma is a malignant tumor of melanocytes residing in skin, mucosal sites, eye, and meninges. In the United States, the incidence is 10-25 per 100,000 persons, with approximately 76,100 new cases of melanoma and 9,710…

Histologic Diagnosis of Inflammatory Skin Diseases

Melanocytes

Melanocytes synthesize melanin. From precursors in the neural crest, melanocytes migrate normally to the epidermis, the bulb of hair follicles, epithelia of various mucous membranes, leptomeninges, inner ear, and a few other tissues (Fig. 1.61). Pri…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Blue Nevus?

…ue naevus.’ In the common variety bipolar and dendritic melanocytes lie singly or in masses in the dermis. . . . The cellular type is composed of the same elements as the ordinary type, but in addition possesses islands of larger cells arranged…

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