Search Results for: melanocytes

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Therapeutic Strategies in Dermatology

Melanoma: Key Points

…e management of metastatic melanoma and extend survival for affected patients. Introduction Melanoma is a malignant tumor of melanocytes residing in skin, mucosal sites, eye, and meninges. In the United States, the incidence is 10-25 per 100,000…

Therapeutic Strategies in Dermatology

Facial Melanosis, Melasma: Key Points

…er cutaneous lip. It results from increased epidermal melanin pigment in the epidermis, dermis, or both; increased number of melanocytes or dermal melanophages in the dermis may also result in melasma. It usually appears in association with estrogen…

Histologic Diagnosis of Inflammatory Skin Diseases

Melanocytes

…on of the body, being more numerous in the skin of the face (up to 2,900 melanocytes per mm2) than on the trunk (up to 1,250 melanocytes per mm2). Figure 1.62 Epidermal melanocytes, when viewed through a conventional microscope, appear as…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Blue Nevus?

…by the presence in the dermis (and sometimes in tissues beneath it) of at least some markedly pigmented, bipolar, dendritic melanocytes and by the absence of discrete nests of melanocytes from the epidermis and the dermis. Our cumbersome definition…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo?

…to a distinctive brown macule that occurs on an oral lip and is characterized histopathologically by an increased number of melanocytes present entirely at the junction of epithelium and lamina propria. The melanocytes in the hyperpigmented…

Pigmented Lesions

Pigmented Lesions

…of the dermis is widened by them. A few melanocytes may be present in the uppermost part of the reticular dermis. Nuclei of melanocytes are small and monomorphic. The large nests of melanocytes sometimes are confined entirely to the epidermis….

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