A Clinical Atlas of 101 Common Skin Diseases

Melasma

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Pigmented macules and patches mostly in the middle third of the face, vertically and horizontally, distributed symmetrically and occurring mainly in postpubescent women as a consequence of the combined effects of estrogen and ultraviolet light on melanocytes.

A Clinical Atlas of 101 Common Skin Diseases

Melasma

Pigmented macules and patches mostly in the middle third of the face, vertically and horizontally, distributed symmetrically and occurring mainly in postpubescent women as a consequence of the combined effects of estrogen and ultraviolet light on me…

Therapeutic Strategies in Dermatology

Facial Melanosis, Melasma

Pigmented macules and patches mostly in the middle third of the face, vertically and horizontally, distributed symmetrically and occurring mainly in postpubescent women as a consequence of the combined effects of estrogen and ultraviolet light on me…

Therapeutic Strategies in Dermatology

Facial Melanosis, Melasma: Key Points

Key Points Facial melanosis (also known as melasma) is a very common condition. In the USA, 5 to 6 million individuals are affected. Melasma usually appears in association with oral contraceptive (OCP) use or pregnancy (“chloasma,” or t…

Therapeutic Strategies in Dermatology

Facial Melanosis, Melasma: Treatment

Treatment The therapeutic strategy is to remove the underlying cause (if known), bleach the pigmentation, and prevent the formation of new pigment by reducing and blocking sun exposure. First-line therapy: First-line treatment is a triple combinatio…

Therapeutic Strategies in Dermatology

Facial Melanosis, Melasma: References

…rtnam R, Halpern J, Salim A, Emmett C (2010) Interventions for melasma, Cochrane Database of Systematic Reviews, 7: ArtCD003583. Pandya AG et al (2011) Reliability assessment and validation of the Melasma Area and Severity Index (MASI) and a new modi…

Therapeutic Strategies in Dermatology

Facial Melanosis, Melasma: Clinical Case

Clinical Case 32-year-old healthy woman Six months’ history of progressively darkening skin on the forehead, lateral cheeks, nose Does not wear daily sunscreen Exercises several times a week outdoors without sunscreen Started taking e…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Erythema Dyschromicum Perstans?

“During the year 1959–1960 in the Department of Dermatology of the Vargas Hospital in Caracas, we studied five adult patients with a peculiar new pigmentary disorder. . . . The skin eruption is characterized by numerous macules with a…