A Clinical Atlas of 101 Common Skin Diseases

Sarcoidosis

…that involves, among other organs, the lungs, lymph nodes, and skin, and the latter in the form usually of papules, sometimes in arcuate and annular configuration, especially on a face, but also on the extremities, and often in pre-existing scars. In…

Histologic Diagnosis of Inflammatory Skin Diseases

Leprosy

…ng suspected by virtue of those characteristics discernible in sections stained by hematoxylin and eosin. In this context, the meaning of the term “tubercle” deserves amplification. In classic pathology, tubercles referred to the gross ap…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…omatous + 10.95.2B: Collection of epithelioid histiocytes, some cells of which are multinucleate, in association with a few lymphocytes = Sarcoidosis ┬áThe near absence of lymphocytes from the vicinity of epithelioid tubercles is characteristic of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

-oid?

…devoid of an enveloping mantle of lymphocytes (so-called naked tubercles). Granulomas in sarcoidosis may be tuberculoid, i.e., epithelioid tubercles surrounded by dense infiltrates of lymphocytes, e.g., as in subcutaneous sarcoidosis. Paradoxically,…

Histologic Diagnosis of Inflammatory Skin Diseases

Sebaceous Units

…ng at the junction of infundibulum and isthmus (Fig. 1.43). On some sites, e.g., the buccal mucosa and vermilion of the lip (Fordyce’s spots), areolae of women (Montgomerys tubercles), labia minora and glans (Tyson’s glands), and e…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Ichthyoses?

…xeroderma, ichthyosis nitida, ichthyosis nigricans, ichthyosis serpentine, ichthyosis sauriasis, and ichthyosis hystrix, the latter two conditions combined by him under the name “ichthyosis cornea.” Ormsby and Montgomery classified the ic…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…0-06. Hu CH, Winkelmann RK. Digitate dermatosis, a new look at symmetrical, small plaque parapsoriasis. Arch Dermatol 1973;107:65-69. Hyde JN, Montgomery FH. A contribution to the study of the so-called premycosis stage of mycosis fungoides. Am Derma…

Differential Diagnosis in Dermatopathology

Tuberculoid leprosy vs. Sarcoidosis

…that involves, among other organs, the lungs, lymph nodes, and skin, and the latter in the form usually of papules, sometimes in arcuate and annular configuration, especially on a face, but also on the extremities, and often in pre-existing scars. In…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum

…longer are present. Another challenge in diagnosis is posed by sarcoidosis when it is composed of “naked” tubercles of epithelioid histiocytes that are dispersed throughout lobules, as well as housed in fibrous septa, a combination of fin…

Differential Diagnosis in Dermatopathology

Discussions

…ris than it does tuberculoid leprosy. Episodically, lesions of sarcoidosis may consist of dense infiltrates of lymphocytes in conjunction with epithelioid tubercles. In such instances, it may not be possible to differentiate histopathologically among…