Search Results for: mucin

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Therapeutic Strategies in Dermatology

Lupus: Key Points

…vacuolar interface dermatitis, often in association with a lymphocytic infiltrate with plasma cells, epidermal atrophy, and mucin. Variants exist, such as bullous lupus, which is marked by the presence of bullous lesions clinically and…

A Clinical Atlas of 101 Common Skin Diseases

Lupus Erythematosus

An inflammatory process that expresses itself in the skin in protean ways that are variations on a basic pathologic theme, and includes evanescent patches on the face (“butterfly blush”), scaly papules and plaques that resolve with…

Therapeutic Strategies in Dermatology

Granuloma Annulare: Key Points

Key Points Granuloma annulare is a reactive inflammatory skin condition, which commonly presents as annular pink, erythematous thin plaques on the distal extremities. Granuloma annulare usually presents as localized disease, generalized plaques or…

Therapeutic Strategies in Dermatology

Dermatomyositis: Key Points

…matitis with lymphocytes tagging the basal keratinocytes at the dermal/epidermal junction, accompanied by varying amounts of mucin. Notably, biopsy cannot distinguish between dermatomyositis and lupus. Therapy of dermatomyositis is determined by…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…red a riveting aquamarine by the colloidal iron stain. In contrast to the situation in granuloma annulare, where deposits of mucin in foci are invariable, no mucin is detectable in association with the granulomas of necrobiosis lipoidica. 10.43.4A:…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…f junction, and thin epidermis = Lupus erythematosus, discoid Pallor throughout the reticular dermis is a result of abundant mucin there. Deposits of mucin like these may be seen in dermatomyositis, but the density of the infiltrate of lymphocytes…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Myxoma?

…mas, i.e., neoplasms of mucin, only a constellation of benign and malignant neoplasms associated with variable quantities of mucin. Focal mucinosis is neither a myxoid cyst nor a myxoma; it is a huge deposit of mucin. “It seems necessary first…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…of lymphocytes, vacuolar alteration, and a thinned epidermis sometimes = Lupus erythematosus     Connective Tissue Mucinosis in Conjunction with Infiltrates of Inflammatory Cells Abundant mucin in the reticular dermis in association with…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…te/subacute discoid lupus erythematosus in which the surface of papules and plaques is smooth and devoid of scale. So-called mucinosis lupus erythematosus can be conceived of as a caricature of lupus tumidus, the amount of mucin in the reticular…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ytes in a zone of epithelial (infundibular) mucinosis = Mycosis fungoides, alopecia mucinosa expression So-called follicular mucinosis really is mucinosis that affects infundibula and sebaceous lobules more often than it does follicles. That…

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