Search Results for: mucin

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Therapeutic Strategies in Dermatology

Lupus: Key Points

…phocytic infiltrate with plasma cells, epidermal atrophy, and mucin. Variants exist, such as bullous lupus, which is marked by the presence of bullous lesions clinically and histologically, the infiltrate of which may be comprised of neutrophils rath…

A Clinical Atlas of 101 Common Skin Diseases

Lupus Erythematosus

An inflammatory process that expresses itself in the skin in protean ways that are variations on a basic pathologic theme, and includes evanescent patches on the face (“butterfly blush”), scaly papules and plaques that resolve with atrop…

Therapeutic Strategies in Dermatology

Granuloma Annulare: Key Points

Key Points Granuloma annulare is a reactive inflammatory skin condition, which commonly presents as annular pink, erythematous thin plaques on the distal extremities. Granuloma annulare usually presents as localized disease, generalized plaques or p…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…and palisaded array of histiocytes around loci of deposits of mucin and degeneration of collagen = Granuloma annulare This is a presentation stereotypical of granuloma annulare showing both the palisaded and interstitial patterns of granulomatous inf…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…oepidermal junction, focally thinned epidermis, and plentiful mucin throughout the dermis = Lupus erythematosus, discoid  The presence of parakeratosis does not militate against a diagnosis of discoid lupus erythematosus. In fact, it is a common find…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Myxoma?

…), and also in the jaw bones, and encysted in the skin (focal mucinosis) and dorsal wrist ganglion.” Stedman TL. Stedman’s Medical Dictionary. 25th ed. Baltimore, MD: Williams & Wilkins, 1990:1020. “Lastly, neoplastic-hamartomat…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…21; of neutrophils in the papillary and reticular dermis plus mucin increased in the reticular dermis = Bullous lupus erythematosus + Neutrophils, band neutrophils, and nuclear “dust” of neutrophils in dermal papillae and in conjunction w…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…cluding subacute cutaneous Chronic Variations Tumidus, “mucinosis,” and reticulated erythematosus mucinosis (REM) Hypertrophic (verrucous) Pernio (chilblains) Degos’ disease (malignant atrophic papulosis) Subcutaneous (and cutaneous…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…perifolliculosis” + 11.14.9B: Epithelial (infundibular) mucinosis in company with an infiltrate of small lymphocytes and eosinophils = Mycosis fungoides, alopecia mucinosa expression  The infiltrate is present not only in the dermis, but also i…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Infiltration of Jessner?

…can be identified for what it is by the presence of abundant mucin in the reticular dermis. Erythema figuratum cannot be differentiated histopathologically from lesions of polymorphous light eruption devoid of edema or from those of tumid lupus eryt…

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