Search Results for: nerves

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Histologic Diagnosis of Inflammatory Skin Diseases

Nerves

Both somatic sensory and autonomic motor nerves are present in skin (Fig. 1.82). The somatic sensory system mediates sensations of pain, itch, temperature, light touch, discriminative touch, pressure, vibration, and proprioception. Nerves of the aut…

A Clinical Atlas of 101 Common Skin Diseases

Neurofibromatosis

…accompanied by neoplasms with neural differentiation that are situated in nerves (e.g., acoustic neuroma) and in the brain (e.g., gliomas), as well as by manifestations of various kinds in the eyes (e.g., Lisch nodules) and bones (e.g., scoliosis)….

A Clinical Atlas of 101 Common Skin Diseases

Leprosy

An inflammatory disease caused by Mycobacterium leprae. It can involve internal organs or be localized to the skin, where its clinical presentation is dependent on the immunologic status of the host. Persons who are competent immunologically have pa…

Dermatology Practical & Conceptual

Notalgia paresthetica: the unreachable itch

…ringall and colleagues suggested a proliferation of cutaneous nerves in NP lesions [5]. This finding was not confirmed in any of the 14 patients Savk et al biopsied; none of the tissue samples showed an increase in dermal innervation compared with co…

Dermatology Practical & Conceptual

Enlarging plaque on the face with enlarged supraorbital nerve

…to impairments and permanent disability [1]. The most common nerves involved in RR are the median, radial and ulnar nerves, the sural, posterior tibial and perineal nerves, great auricular and the facial nerve. In all leprosy patients, accurate neur…

Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

…crine units, and nail units, come from ectoderm. Melanocytes, nerves, and specialized sensory receptors develop from neuroectoderm. The other elements in skin, i.e., Langerhans” cells, macrophages, mast cells, fibrocytes, blood vessels, lymph v…

Histologic Diagnosis of Inflammatory Skin Diseases

Leprosy

…of more dense infiltrates of lymphocytes that spare cutaneous nerves. Polymorphous light eruption differs from indeterminate leprosy by the presence, often, of notable edema in the papillary dermis. The tumid variant of discoid lupus erythematosus di…

Differential Diagnosis in Dermatopathology

Tuberculoid leprosy vs. Sarcoidosis

An inflammatory disease caused by Mycobacterium leprae. It can involve internal organs or be localized to the skin, where its clinical presentation is dependent on the immunologic status of the host. Persons who are competent immunologically have pa…

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