A Clinical Atlas of 101 Common Skin Diseases

Neurofibromatosis

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A constellation of lesions that represent disorders of melanocytes (e.g., axillary “freckles” and café au lait “spots”) and of proliferations of Schwann cells (e.g., papules, nodules, and tumors of neurofibroma).

A Clinical Atlas of 101 Common Skin Diseases

Neurofibromatosis

…tions of Schwann cells (e.g., papules, nodules, and tumors of neurofibroma). The cutaneous lesions may be accompanied by neoplasms with neural differentiation that are situated in nerves (e.g., acoustic neuroma) and in the brain (e.g., gliomas), as w…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Halo Phenomenon?

…on may occur around a variety of pigmented lesions, including neurofibroma, flat warts, neurotized nevus, blue nevus, garment nevus, Spitz nevus, and melanoma (primary tumor or cutaneous metastases).” Ortonne JP, Mosher DB, Fitzpatrick TB. Vit…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Study By Disease

…thogranuloma (Quiz #680) Neuroendocrine carcinoma (Quiz #730) Neurofibroma (Quiz #527) Neurofibroma (Quiz #528) Neurofibroma (Quiz #529) Neurofibroma (Quiz #674) Nevoid hyperkeratosis of the nipple (Quiz #443) Nevus flammeus (Quiz #416) Nevus of Ito…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Myxoma?

…s have offered alternative names. The terms bizarre cutaneous neurofibroma, Pacinian neurofibroma, neurothekeoma, and myxoid tumor of nerve sheath are synonyms for nerve-sheath myxoma.” Pulitzer DR, Reed RJ. Nerve-sheath myxoma (perineural myx…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Blue Nevus?

…lands of larger cells arranged in a neuroid (‘pigmented neurofibroma’) or sarcomatoid fashion.” MacKie RM. Melanocytic naevi and malignant melanoma. In: Textbook of Dermatology. 5th ed. Oxford, England: Blackwell Scientific Publica…

Dermatology Practical & Conceptual

Melanoma arising in a giant nevus spilus maculosus

…sis (PUL), which seems to be a mosaic manifestation of type 1 neurofibromatosis [5]. This rare condition was excluded on the basis of clinical findings because in PUL the background is normal and not hyperpigmented and the body-midline is not crossed…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Metastasizing Dermatofibroma?

…ists in general, a term that ends in -oma, such as leiomyoma, neurofibroma, or hemangioma, denotes a neoplasm. In actuality, dermatofibroma is a type of fibrosing inflammation that has no potential whatsoever for metastasis. The determination that de…