A Clinical Atlas of 101 Common Skin Diseases

Neurofibromatosis

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A constellation of lesions that represent disorders of melanocytes (e.g., axillary "freckles" and café au lait "spots") and of proliferations of Schwann cells (e.g., papules, nodules, and tumors of neurofibroma).

A Clinical Atlas of 101 Common Skin Diseases

Neurofibromatosis

A constellation of lesions that represent disorders of melanocytes (e.g., axillary "freckles" and café au lait "spots") and of proliferations of Schwann cells (e.g., papules, nodules, and tumors of neurofibroma). The cutaneous lesions may be accompanied by neoplasms with neural differentiation that are situated in nerves (e.g., acoustic neuroma) and in the brain (e.g., gliomas), […]

Dermatology Practical & Conceptual

Systemic mastocytosis associated with chronic myelomonocytic leukemia and xanthogranuloma

Abstract   A patient with a history of non-diagnostic bone marrow biopsies presented with a red to brown maculopapular rash on the back. Biopsies confirmed multiple xanthogranulomas as well as a mastocytosis. A consequently performed bone marrow biopsy verified a systemic mastocytosis and a chronic myelomonocytic leukemia (CMML) type I. Here, we describe for the […]

Histologic Diagnosis of Inflammatory Skin Diseases

Xanthogranuloma

Xanthogranuloma Synonyms Juvenile xanthogranuloma Nevoxanthoendothelioma Nevoxanthoma Juvenile xanthoma Juvenile giant cell granuloma Xanthoma multiplex Multiple eruptive xanthoma in infancy Congenital xanthoma tuberosum Xanthoma naeviforme Presen…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Dermatology Practical & Conceptual

Melanoma arising in a giant nevus spilus maculosus

Abstract Melanoma arising in a nevus spilus is rare. There are two distinct types of nevus spilus characterized by macular or papular speckles, respectively. We report the case of a melanoma that arose in association with a giant nevus spilus maculo…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Wide and Deep Excision for Melanoma?

“Widths of excision as much as 100 mm from the edge of the lesion have been advocated and most surgeons have practiced wide excision with a 50-mm margin area without anatomical limitations.” McLeod GRC. Malignant melanoma: primary trea…