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Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Key Points

Key Points Hidradenitis suppurativa (HS) is a chronic inflammatory process affecting skin bearing apocrine glands; the groin, axillae, and inframammary areas are typically involved. The classic lesions of HS include cysts, nodules, sinus tracts, an…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: References

…husayen, R., Shear, N.J. (2012) Pharmacologic intervention for hidradenitis suppurativa: what does the evidence say? Amer J Clin Derm, 13: 283-291. Alikhan, A., Lynch, P.J., Eisen, D.B. (2009) Hidradenitis suppurativa: a comprehensive review (CME), J…

Therapeutic Strategies in Dermatology

Sweet’s Syndrome (Acute Febrile Neutrophil Dermatosis): Key Points

Key Points Indurated, often painful, erythematous nodules are the characteristic skin lesion that marks Sweet’s syndrome. Skin lesions may be bullous or cellulitis-like (pseudocellulitic) in appearance. Skin lesions of Sweet’s syndrome are often ac…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Treatment

Treatment First-line therapy: The first-line therapy for mild to moderate hidradenitis suppurativa is topical or systemic antibiotics. For very severe disease, systemic immunosuppression, specifically with anti-TNF-alpha inhibitors, may be first-lin…

Therapeutic Strategies in Dermatology

Alopecia: Key Points

Key Points Alopecia, or hair loss, has a broad spectrum of causes. In order to appropriately treat alopecia, the type of hair loss or pathophysiology must be clearly identified. The evaluation for hair loss requires a very thorough history and phys…

Therapeutic Strategies in Dermatology

Sweet’s Syndrome (Acute Febrile Neutrophil Dermatosis): References

References Brinster NK et al (2012) Nonbullous neutrophilic lupus erythematosus: a newly recognized variant of cutaneous lupus erythematosus, JAAD, 66(1):92-97. Dabade TS, Davis MD (2011) Diagnosis and treatment of the neutrophilic dermatoses (pyode…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Key Points

Key Points Pyoderma gangrenosum is a type of ulcerating neutrophilic dermatosis. The classic morphology of pyoderma gangrenosum is an ulcer with a violaceous rim and undermined border. PG lesions may develop very rapidly (in days) and may be trigg…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Clinical Cases

Clinical Cases Case 1 27-year-old female No significant past medical history and she takes no medications Denies GI symptoms Presents for management of painful cysts on bilateral axilla with purulent drainage Initial evaluation Obese young fem…

Therapeutic Strategies in Dermatology

Appendigeal Tumors: Overview

Adnexal Tumors Both benign and malignant tumors may arise from the cutaneous adnexa (hair follicles, sweat glands, and sebaceous glands). Treatment First Steps A biopsy is usually necessary to establish the diagnosis, except for syringomas. Surgica…

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