Therapeutic Strategies in Dermatology

Extramammary Paget’s/Paget’s Disease: Overview

Overview The diagnosis of Paget’s disease or extramammary Paget’s is made when Paget cells are identified in histopathologic specimens from involved skin. The term Paget’s disease is used when the cutaneous lesion is identified inv…

A Clinical Atlas of 101 Common Skin Diseases

Mammary Paget’s

Mammary Paget’s disease is an apocrine carcinoma that begins in mammary glands and extends along lactiferous ducts to the epidermis where it is seen clinically as a scaly, crusted, or eroded plaque on the nipple or areola of women mostly, and…

Therapeutic Strategies in Dermatology

Borreliosis (Lyme Disease): Initial Evaluation

Initial Evaluation Erythema chronicum migrans Acrodermatitis chronica atrophicans These lesions may occur at the sites of prior erythema chronicum migrans. Atrophic epidermis is the hallmark. Sclerodermatous changes, with thickening a…

A Clinical Atlas of 101 Common Skin Diseases

Scabies

An inflammatory process caused by the acarus Sarcoptes scabiei and consisting of papules, papulovesicles, papulopustules, and vesicles, some arranged in linear or curvilinear tracks (burrows). Sometimes nodules are present, especially in the interdi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mammary and Extramammary Paget’s Disease?

“Extramammary Paget’s disease is a carcinoma of the ducts of apocrine sweat glands, with the invasion of carcinoma cells (Paget’s cells) into the epidermis and into the glandular portion of the sweat gland.” Braun-Falco O,…

Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

All constituents of human skin are derived from either ectoderm or mesoderm. The epithelial structures, i.e., epidermis (surface and infundibular), apocrine units, sebaceous units, hair follicles, eccrine units, and nail units, come from ectoderm. M…

Differential Diagnosis in Dermatopathology

Syringocystadenoma papilliferum vs. Hidradenoma papilliferum

An inflammatory process caused by the acarus Sarcoptes scabiei and consisting of papules, papulovesicles, papulopustules, and vesicles, some arranged in linear or curvilinear tracks (burrows). Sometimes nodules are present, especially in the interdi…

Differential Diagnosis in Dermatopathology

Discussions

…analogue of hidradenoma papilliferum that may be situated on a nipple. This cystic adenoma is known by a variety of names, among them nipple adenoma, subareolar papillomatosis, and erosive adenomatosis. For many years it was considered to be a pseudo…