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A Clinical Atlas of 101 Common Skin Diseases

Pemphigus Foliaceus

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A blistering inflammatory disease in which acantholysis occurs in the upper part of the spinous zone or granular zone of the epidermis, the result of the process being flaccid blisters that give way to erosions and crusts accompanied by erythema.

A Clinical Atlas of 101 Common Skin Diseases

Pemphigus Vulgaris

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A blistering disease of skin and mucous membranes that presents itself in the skin first as flaccid bullae that soon become eroded, and in mucous membranes as erosions, hemorrhagic crusts, or both.

A Clinical Atlas of 101 Common Skin Diseases

Pemphigus Foliaceus

A blistering inflammatory disease in which acantholysis occurs in the upper part of the spinous zone or granular zone of the epidermis, the result of the process being flaccid blisters that give way to erosions and crusts accompanied by erythema. Wh…

A Clinical Atlas of 101 Common Skin Diseases

Pemphigus Vulgaris

A blistering disease of skin and mucous membranes that presents itself in the skin first as flaccid bullae that soon become eroded, and in mucous membranes as erosions, hemorrhagic crusts, or both. If widespread and untreated, the disease can be fat…

Therapeutic Strategies in Dermatology

Pemphigus Foliaceus, Pemphigus Erythematosus

A blistering disease of skin and mucous membranes that presents itself in the skin first as flaccid bullae that soon become eroded, and in mucous membranes as erosions, hemorrhagic crusts, or both. If widespread and untreated, the disease can be fat…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris

A blistering disease of skin and mucous membranes that presents itself in the skin first as flaccid bullae that soon become eroded, and in mucous membranes as erosions, hemorrhagic crusts, or both. If widespread and untreated, the disease can be fat…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris: Overview

…lications of immunosuppression and high-dose steroid therapy. Paraneoplastic Pemphigus Paraneoplastic pemphigus is associated with an underlying malignancy (usually lymphoma) or with Castleman’s disease (especially in children). It is very ref…

Therapeutic Strategies in Dermatology

Pemphigus Foliaceus, Pemphigus Erythematosus: Overview

Overview Pemphigus foliaceus is a relatively benign autoimmune bullous disease associated with the deposition of intercellular antibodies directed against desmoglien 1. The therapeutic approach differs significantly from that for pemphigus vulgaris;…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Paraneoplastic Pemphigus?

…higus vulgaris antigen) are present in sera from patients with paraneoplastic pemphigus and cause acantholysis in vivo in neonatal mice. J Clin Invest 1998;102:775–82. In their original publication about paraneoplastic pemphigus, Anhalt et al. wrote…

Histologic Diagnosis of Inflammatory Skin Diseases

Paraneoplastic pemphigus

Paraneoplastic pemphigus Presentation stereotypical Age and sex Elderly persons who suffer from a malignant neoplastic process such as lymphoma, leukemia, thymoma, or Castleman’s disease Distribution of lesions Widespread; usually severe invol…

Histologic Diagnosis of Inflammatory Skin Diseases

Paraneoplastic pemphigus

A blistering disease of skin and mucous membranes that presents itself in the skin first as flaccid bullae that soon become eroded, and in mucous membranes as erosions, hemorrhagic crusts, or both. If widespread and untreated, the disease can be fat…

A Clinical Atlas of 101 Common Skin Diseases

Hailey-Hailey Disease

A vesiculobullous disease in which blisters tend to be flaccid and localized to intertriginous regions, especially, the neck, axillary, inframammary, and inguinal ones. The disease is notoriously refractory to therapy. The name originally given to t…

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