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A Clinical Atlas of 101 Common Skin Diseases

Bullous Pemphigoid and Herpes Gestationis

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An inflammatory disease of older people; signs include widespread erythematous macules and patches, urticarial papules and plaques, and vesicles and bullae, the blisters often arising on urticarial plaques.

A Clinical Atlas of 101 Common Skin Diseases

Bullous Pemphigoid and Herpes Gestationis

…sicles and bullae, the blisters often arising on urticarial plaques. Sometimes lesions are localized, e.g., to the legs. The cause is not known, but the mechanism is thought to be immunologic in response to antibodies to bullous pemphigoid antigens….

Therapeutic Strategies in Dermatology

Cicatricial Pemphigoid

…sicles and bullae, the blisters often arising on urticarial plaques. Sometimes lesions are localized, e.g., to the legs. The cause is not known, but the mechanism is thought to be immunologic in response to antibodies to bullous pemphigoid antigens….

Therapeutic Strategies in Dermatology

Herpes Gestationis/Pemphigoid Gestationis

…sicles and bullae, the blisters often arising on urticarial plaques. Sometimes lesions are localized, e.g., to the legs. The cause is not known, but the mechanism is thought to be immunologic in response to antibodies to bullous pemphigoid antigens….

Therapeutic Strategies in Dermatology

Bullous Pemphigoid

…sicles and bullae, the blisters often arising on urticarial plaques. Sometimes lesions are localized, e.g., to the legs. The cause is not known, but the mechanism is thought to be immunologic in response to antibodies to bullous pemphigoid antigens….

Therapeutic Strategies in Dermatology

Bullous Pemphigoid: Overview

Overview Bullous pemphigoid is usually a self-limited inflammatory subepidermal blistering disorder of the elderly, in which circulating auto antibodies to epitopes in the basement membrane zone bind to this region and initiate a cascade of inflamma…

Therapeutic Strategies in Dermatology

Epidermolysis Bullosa Acquisita: Overview

…n inflammatory bullous disorder clinically similar to bullous pemphigoid, cicatricial pemphigoid, localized scarring pemphigoid, or linear IgA disease. Diagnosis is confirmed by special immunofluorescent studies using salt split skin, staining of his…

Therapeutic Strategies in Dermatology

Prurigo Nodularis: Overview

…o nerve impingement (brachioradial pruritus). Rarely, bullous pemphigoid may present as prurigo nodularis (pemphigoid nodularis). In some persons, no underlying condition is found. Prurigo nodularis is often very difficult to manage. Treatment Initia…

Therapeutic Strategies in Dermatology

Cicatricial Pemphigoid: Overview

Overview Cicatricial pemphigoid is a chronic, scarring, subepithelial bullous disorder that affects mucous membranes, including the conjunctivae. This disorder is thought to be mediated by autoantibodies directed at antigens in the epithelial baseme…

Therapeutic Strategies in Dermatology

Chronic Bullous Disease of Childhood: Overview

…ment membrane zone. The clinical appearance resembles bullous pemphigoid. It often remits 2-3 years after onset and rarely lasts past age 10. Because this disorder affects children and is most frequently self-limited, the therapeutic strategy is to e…

Therapeutic Strategies in Dermatology

Linear IgA Dermatosis: Overview

…s disorder that resembles dermatitis herpetiformis or bullous pemphigoid but is distinguished from these disorders by the linear deposition of IgA at the epidermodermal junction and the absence of gluten-sensitive enteropathy. Many cases are drug-ind…

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