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Therapeutic Strategies in Dermatology

Melanoma: Key Points

Key Points The therapy of malignant melanoma is determined by the histopathologic features (primarily tumor thickness, ulceration, regression, and mitotic index), by the location of the tumor, by the presence of regional or distant metastases and b…

Therapeutic Strategies in Dermatology

Melanoma: Treatment

Treatment Initial therapy First-line therapy: Surgical excision For diagnosis, complete excisional biopsy with minimal margins, pathologically evaluated at multiple levels to determine the tumor thickness, as well as to determine presence of ulcera…

Therapeutic Strategies in Dermatology

Vascular Birthmarks: Key Points

Key Points Vascular birthmarks are cutaneous vascular lesions present at, or shortly after, birth. They may be categorized as vascular tumors or vascular malformations. The term hemangioma has previously been used to describe many common, typicall…

Therapeutic Strategies in Dermatology

Flushing: Clinical Case

…aring woman without flushing nor telangiectasias of the face (she reports that she is currently asymptomatic) Vitals: slight tachycardia, otherwise normal No thyromegaly or abdominal masses noted History and exam is concerning for carcinoid tumor syn…

Therapeutic Strategies in Dermatology

Psoriasis: Principles of Psoriasis Management

…oriasis is primarily a T lymphocyte driven, immune-mediated disorder. The development of a new class of drugs, engineered proteins targeting specific immunologic mediators involved in psoriasis, including tumor necrosis factor alpha (TNF-A), may offe…

A Clinical Atlas of 101 Common Skin Diseases

Melanoma

…lat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly shades of brown. A patch may become a plaque or upon it may develop a papule, nodule, or tumor. A papule may deve…

Differential Diagnosis in Dermatopathology

Apocrine mixed tumor vs. Eccrine mixed tumor

…lat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly shades of brown. A patch may become a plaque or upon it may develop a papule, nodule, or tumor. A papule may deve…

Therapeutic Strategies in Dermatology

Erythema Annulare Centrifugum: Overview

…with internal malignancy; erythema chronicum migrans, which is the primary stage of Lyme disease; erythema marginatum, which occurs with acute rheumatic fever; and necrolytic migratory erythema, which is associated with a glucagon-secreting tumor. T…

Therapeutic Strategies in Dermatology

Impetigo: Key Points

…15 years (Koning et al., McCormick et al.). The two major forms of impetigo, bullous impetigo and impetigo contagiosum, can masquerade as noninfectious diseases, as both may lack characteristic signs of acute infection (i.e., dolor, calor, tumor, and…

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