Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eosinophilic Cellulitis (Wells’ Syndrome)?

“This is a study of the clinical features of four patients in the light of particular cutaneous histopathology. The characteristic eruption is periodic, tending to recur every few months, usually without systemic symptoms. The acute state of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Sclerotic Fibroma?

“Nine biopsies revealed a distinctive type of fibroma characterized by an organized pattern of interwoven fascicles of collagen bundles with a laminated or tortuous appearance, embedded in abundant mucin. A number of fibromas showed striking…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

“The occurrence of a clinical syndrome of severe asthma, fever, and hypereosinophilia, together with symptoms of vascular embarrassment in various organ systems, has been established. . . . The basic anatomical changes . . . consisted of wide…

Differential Diagnosis in Dermatopathology

Discussions

The most important finding that granular-cell tumors and xanthomas have in common is diffuse dermal infiltrates of monomorphous cells that possess abundant pale-staining cytoplasm. The cytoplasm may have either a basophilic or eosinophilic hue in se…