Histologic Diagnosis of Inflammatory Skin Diseases

Scleromyxedema

Scleromyxedema Synonyms Papular mucinosis Lichen myxedematosus Presentation stereotypical Age and sex Adults of either sex Distribution of lesions Widespread Individual lesions Papules that produce diffuse thickening of the skin Course Protracted Va…

Histologic Diagnosis of Inflammatory Skin Diseases

Nephrogenic fibrosing dermopathy

…of extremities, but is unassociated with papules and nodules. Scleromyxedema is typified by papules and plaques positioned on the face, arms, and hands, less commonly on legs and trunk, and by association with paraproteinemia Findings histopathologi…

Differential Diagnosis in Dermatopathology

Discussions

Pretibial myxedema and scleromyxedema are more alike in name than they are in findings histopathologic. In a sense, however, both are cutaneous mucinoses in which an increased number of fibrocytes and mast cells are present in zones that house acid…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…s known as focal mucinosis, myxedema, pretibial myxedema, and scleromyxedema. Error: Dermatofibroma is a neoplasm. Reason: It is a fibrosing dermatitis that goes by a variety of other ill-conceived names such as sclerosing hemangioma, histiocytoma, a…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ndle- and stellate-shaped fibrocytes, as well as mast cells = Scleromyxedema, early ┬áThis is an early lesion because mucin is so abundant in the reticular dermis. A synonym for the condition is papular mucinosis, another is lichen myxedematosus. Irre…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ems, however, to be unique, surely different from morphea and scleromyxedema. 10.69.2A: Fibrosing dermatitis, panniculitis, septal, and fasciitis + 10.69.2B: Fibrocytes scattered among wavy bundles of collagen = Nephrogenic fibrosing dermop…