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Therapeutic Strategies in Dermatology

Persistent Pigmented Purpuric Dermatitis: Overview

…iew This group of diseases includes Schamberg’s disease, purpura annularis telangiectodes (of Majocchi), lichenoid pigmented purpura (of Gougerot and Blum), eczematoid purpura of Doucas and Kapetanakis (disseminated pruriginous angiodermatitis)…

Therapeutic Strategies in Dermatology

Lichen Planus: Initial Evaluation

Initial Evaluation Lesions of lichen planus are marked by violaceous-to-purple flat-topped papules, often with a white-to-lavender reticulate overlying scale (Wickham’s striae). Patients report intense pruritus and sometimes koebnerization (de…

A Clinical Atlas of 101 Common Skin Diseases

Persistent Pigmented Purpuric Dermatitis

An inflammatory process, but not a vasculitis, that involves the legs especially with purpuric macules and subtle papules (Schamberg’s disease), lichenoid papules (lichenoid purpura of Gougerot-Blum), and scaly papules (eczematid-like purpura

A Clinical Atlas of 101 Common Skin Diseases

Allergic (Leukocytoclastic) Vasculitis

A systemic inflammatory process involving venules by deposits of fibrin within their wall in conjunction with neutrophils and nuclear “dust” of neutrophils in the dermis and, at times, the subcutaneous fat. The clinical manifestations ar…

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Treatment

Treatment First-line therapy: The main treatment involves getting the affected areas warm, and keeping them warm. Wet, constrictive clothing should be removed immediately. The affected skin should be kept warm and dry, with loose, layered clothing,…

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Key Points

Key Points Chilblains (pernio) is a benign condition that occurs in cold, damp environments and presents with symmetric, distal, transient red-to-purple lesions on the extremities. Treatment is centered on keeping the patient warm and avoiding expo…

Therapeutic Strategies in Dermatology

Leukocytoclastic Vasculitis: Key Points

Key Points Leukocytoclastic vasculitis (LCV) represents inflammation of small vessels in the skin stemming from immune complex deposition. Clinically, LCV presents with an eruption of palpable monomorphous purpuric papules, which may have central v…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Palpable Purpura?

…the prominent clinical features of leukocytoclastic angiitis. Purpura is almost always present in the cutaneous lesions and is frequently accompanied by evidence of increased vascular permeability. Therefore, purpura, when present, is almost always…

A Clinical Atlas of 101 Common Skin Diseases

Septic Vasculitis

A small-vessel vasculitis characterized clinically by vesiculopustules on an erythematous base, purpuric macules and papules, and hemorrhagic bullae, and histopathologically by thrombi within venules, a consequence of sepsis….

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