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A Clinical Atlas of 101 Common Skin Diseases

Lymphomatoid Papulosis

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A distinctive type of CD 30 lymphoma characterized by the presence mostly of papules, some of them purpuric, that may ulcerate and heal with a scar, and by lesions that tend to come and go for years, eventually disappearing entirely or, on occasion, becoming nodular and even tumorous, which is an indication of likelihood of detectable lymphomatous involvement of some organs besides the skin.

Therapeutic Strategies in Dermatology

Melanoma: Treatment

…be considered for more extensive baseline evaluation such as sentinel lymph node biopsy and/or searching for metastases (CT or MRI of the brain, chest, abdomen or pelvis, or PET CT). Ancillary therapy The decision to pursue regional sentinel lymph

Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides: Overview

…s or plaques < o r> 10% body surface area with palpable lymph nodes without pathologic involvement Stage IIB-tumors with or without palpable lymph nodes in the absence of pathologic involvement Stage III-erythroderma with or without palpable ly…

Therapeutic Strategies in Dermatology

Melanoma: Key Points

…, lactate dehydrogenase. *Micrometastases are diagnosed after sentinel lymph node biopsy.†Macrometastases are defined as clinically detectable nodal metastases confirmed pathologically. Table 2. Depth of melanoma invasion based on histopathologic lev…

Therapeutic Strategies in Dermatology

Melanoma: Clinical Cases

…performed and does not identify any other suspicious lesions Biopsy: melanoma, 2.1 mm thickness Follow-up The patient undergoes wide local excision with 2 cm margins and elects to have sentinel lymph node mapping and dissection, which reveals 2 of…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…or regression in slightly over 50% of patients. For localized lymphatic and mucosal disease, radiation therapy in fractionated doses may help control lymph node disease and the associated lymphedema. Patients with mucosal disease may require signific…

Therapeutic Strategies in Dermatology

Alopecia: Clinical Cases

…ult, ongoing transition to their new home Initial visit No biopsy is indicated; on further questioning, the parents admit that they have noticed their daughter pulling at her hair, especially the eyelashes, when stressed; a diagnosis of trichotill…

Therapeutic Strategies in Dermatology

Melanoma: References

…s, Clinics in Dermatology, 28:311-315. Morton DL et al (2006) Sentinel-node biopsy or nodal observation in melanoma, NEJM, 355:1307-1317. National Cancer Institute. Melanoma Treatment (PDQ). 7 Nov 2014. Web. http: www.cancer.gov/cancertopics/pdq/trea…

Therapeutic Strategies in Dermatology

Alopecia: Key Points

…valuation for hair loss may entail a hair sample mount, scalp biopsy, and/or blood tests to identify a diagnosis or underlying cause. There is not always an effective treatment for hair loss, but identifying the correct underlying process causing alo…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Clinical Cases

…locytes noted on peripheral smear, and widespread mediastinal lymphadenopathy is noted on chest X-ray The patient is referred to hematology/oncology for a bone marrow biopsy Ongoing wound care with clobetasol ointment under occlusion is recommended M…

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