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Therapeutic Strategies in Dermatology

Melanoma: Treatment

…itfalls Failure to accurately diagnose a melanoma. Failure to biopsy a suspicious lesion is the most serious pitfall. An inadequate initial biopsy or pathologic evaluation is a major pitfall that may result in inadequate therapy. Inclusion of at lea…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…. Skin lesions are an excellent source of diagnostic material. Biopsy the thickest nonulcerated lesion. Punch, excision, or shave biopsies (of exophytic nodules) are adequate. Do not biopsy at the edge of skin lesions, but rather in the center. Evalu…

Therapeutic Strategies in Dermatology

Warts: Treatment

…rts in the beard, and women with warts on the legs, should not shave until the lesions are cleared. Electric shavers may reduce this spread. Flat warts may be more prevalent during summer months and in children with outdoor exposure. Patients with fa…

Therapeutic Strategies in Dermatology

Folliculitis (including pseudofolliculitis barbae): Treatment

…essential: Dislodge all ingrown hairs. Soak the beard with a shave cream for several minutes. Shave with the grain using even, smooth strokes. Do not press down with the razor. Do not stretch the skin when shaving. Shave often enough to keep the be…

Therapeutic Strategies in Dermatology

Alopecia: Clinical Cases

…ther manifestations of hyperandrogenism or virilization A skin biopsy is offered to the patient, which she accepts; she is highly-motivated to confirm the diagnosis of androgenetic alopecia; a 4 mm punch biopsy of the affected area of alopecia is per…

Therapeutic Strategies in Dermatology

Alopecia: Key Points

…in the area of hair loss and a diagnosis is not clear, a scalp biopsy and tissue culture is strongly indicated. Evidence of scarring should also prompt a scalp biopsy. There are numerous pathophysiologic mechanisms that result in alopecia: hair shaf…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Clinical Cases

Clinical Cases Case 1 67-year-old male No significant past medical history Review of systems is notable for six-month history of unexplained weight loss, night sweats, fatigue Presents for management of an extremely painful leg ulcer that rapidl…

Therapeutic Strategies in Dermatology

Melanoma: Key Points

Key Points The therapy of malignant melanoma is determined by the histopathologic features (primarily tumor thickness, ulceration, regression, and mitotic index), by the location of the tumor, by the presence of regional or distant metastases and b…

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