Search Results for: sign of leser-trelat

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A Clinical Atlas of 101 Common Skin Diseases


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An inflammatory process that develops secondary to trauma, usually in the form of a penetrating injury or rupture of a follicle, and that proceeds through stages of granulation tissue with numerous extravasated erythrocytes, granulomatous inflammation, and fibrosis.

A Clinical Atlas of 101 Common Skin Diseases

Dermatofibrosarcoma Protuberans

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A malignant nonepithelial neoplasm (a sarcoma) presumably of perineural fibrocytes that presents itself usually on the trunk, but sometimes elsewhere, such as the extremities, face, and scalp.

A Clinical Atlas of 101 Common Skin Diseases


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A constellation of lesions that represent disorders of melanocytes (e.g., axillary “freckles” and café au lait “spots”) and of proliferations of Schwann cells (e.g., papules, nodules, and tumors of neurofibroma).

A Clinical Atlas of 101 Common Skin Diseases

Pruritic Urticarial Papules and Plaques of Pregnancy

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An inflammatory process in pregnant women near term that consists of urticarial papules and plaques, especially on the trunk and particularly in association with lesions of striae atrophicantes, the lesions disappearing shortly after parturition.

Therapeutic Strategies in Dermatology

Dermatomyositis: Key Points

…des of the fingers) Samitz’s sign (ragged, frayed cuticles) Proximal nail fold erythema and periungual telangiectasias Shawl sign (violaceous erythema of the V-neck of the chest and upper back/lateral deltoids) Holster sign (erythema of the lateral…

Therapeutic Strategies in Dermatology

Urticaria Pigmentosa / Mastocytosis: Key Points

…ing molecules, and often results in a localized wheal response, where the lesion while form a hive; this is called “Darier’s sign.” Darier’s sign can be seen in isolated mastocytomas, childhood urticaria pigmentosa, and diffuse cutaneous…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Key Points

…emic immunosuppression to halt progression and promote healing. PG lesions may be exquisitely painful, sometimes out of proportion to their clinical appearance or size; reduction in pain associated with a lesion represents an important early sign of…

Therapeutic Strategies in Dermatology

Keratosis Pilaris: Treatment

…ntaining 20% urea (Carmol) may prevent reappearance of lesions. Use of the abrasive scrub pad should be resumed at the first sign of reappearance of crops of new lesions. Patient education on gentle skin care, including discussion of bathing, mild…

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…ormalities, seizures, and more. Cardiac sarcoidosis is also rare, affecting approximately 5% of patients, but accounts for a significant portion of sarcoidosis-related mortality. Cardiac sarcoidosis is frequently asymptomatic up to the point of…

Therapeutic Strategies in Dermatology

Drug Eruptions: Therapy

…vement include: leukocytosis, eosinophilia, thrombocytopenia, renal impairment, transaminitis, and elevated creatine kinase (sign of myositis). A skin biopsy may be helpful in distinguishing a morbilliform or hypersensitivity reaction from SJS, TEN,…

Therapeutic Strategies in Dermatology

Atopic Dermatitis: Initial Evaluation

…a commonly-affected site. Lichenification resulting in loss of the lateral aspect of the eyebrows, also known as Hertoghe’s sign. Hypopigmented patches with subtle scale in atopic dermatitis, also known as pityriasis alba. Fissuring is common in…

Therapeutic Strategies in Dermatology

Angular Cheilitis: Treatment

…deficiencies) are rare causes of perlèche. Perlèche, especially when unilateral, that fails to respond as expected may be a sign of a mucocutaneous malignancy. In edentulous and immunosuppressed patients, candidiasis may recur very quickly, and…

Therapeutic Strategies in Dermatology

Syphilis (Lues): Key Points

…es by syphilis have been rising over the past decade. It presents across a broad clinical spectrum, including many cutaneous signs, that evolves with the duration of the infection and also correlates with the immune status of the patient. Table 1….

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