Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Clinical Cases

Case 1 27-year-old female No significant past medical history and she takes no medications Denies GI symptoms Presents for management of painful cysts on bilateral axilla with purulent drainage Initial evaluation Obese young female Otherwise h…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Treatment

First-line therapy: The first-line therapy for mild to moderate hidradenitis suppurativa is topical or systemic antibiotics. For very severe disease, systemic immunosuppression, specifically with anti-TNF-alpha inhibitors, may be first-line. First s…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Key Points

Hidradenitis suppurativa (HS) is a chronic inflammatory process affecting skin bearing apocrine glands; the groin, axillae, and inframammary areas are typically involved. The classic lesions of HS include cysts, nodules, sinus tracts, and inflamed…

Therapeutic Strategies in Dermatology

Cheilitis Granulomatosa: Overview

Melkersson- Rosenthal Syndrome Cheilitis granulomatosa is sudden onset of swelling of the lips which progresses to chronic enlargement. The Melkersson-Rosenthal syndrome diagnosis is made when lip enlargement is accompanied by facial paralysis or pa…

A Clinical Atlas of 101 Common Skin Diseases

Acne Vulgaris

A disease of infundibulosebaceous units, especially infundibula, that may manifest itself solely as noninflammatory lesions, i.e., comedones and intact cysts, or as inflammatory lesions, i.e., papules, nodules, and pustules. The process may resolve…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…At that stage, fibrocytes in morphea are decreased in number. SINUS [L. sinus (enclosure with rounded margins)]: An epithelium-lined channel in the skin that opens on the surface, usually through an infundibular ostium (Fig. 3.34). In contrast to a…

Histologic Diagnosis of Inflammatory Skin Diseases

Destombes-Rosai-Dorfman disease

…HR, Blumke S, et al. Lymphadenitis with massive hemophagocytic sinus histiocytosis. Virchows Arch [B] 1972;10:14–29. Olsen EA, Crawford JR, Vollmer RT. Sinus histiocytosis with massive lymphadenopathy. Case report and review of a multisystemic diseas…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Histiocytoses?

“The concept of grouping as related disorders those which feature proliferation of cytologically mature benign histiocytic elements in either localized or more widespread form will be elaborated.” Halprin KM, Lorincz AL. Disseminated x…