Search Results for: spongiosis

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Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

…looned (“ballooning dermatitis”) (see Fig. 5.20), spongiosis is discernible (“spongiotic dermatitis”) (see Fig. 5.21), or psoriasiform acanthosis is apparent (“psoriasiform dermatitis”) (see Fig. 5.22). Not uncommo…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vesicular Dermatitis

…ticular mechanism responsible for development of the blister (spongiosis [Fig. 5.241A ], ballooning [Fig. 5.241B ], and acantholysis [Fig. 5.241C]). When, in the equation, changes such as attributes cytopathologic of keratocytes (e.g., steel gray nuc…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ary in the basal layer in foci, and in association with scant spongiosis in the spinous zone = Mycosis fungoides, patch  The diagnosis of mycosis fungoides can be made from findings in the epidermis alone, as shown here. Note the absence of any colle…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…filtrate of lymphocytes, edema of the papillary dermis, focal spongiosis and scale-crust, and variable number of extravasated erythrocytes = Gianotti-Crosti syndrome + Wedge-shaped infiltrate, strikingly atypical lymphocytes, and some lymphocytes oft…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…later as collarettes of scale, the latter being testimony to spongiosis having been present within the epidermis, the collarettes representing the residuum of a mound of parakeratosis that largely desquamated. A plaque of nummular dermatitis is give…

Histologic Diagnosis of Inflammatory Skin Diseases

Infundibulofolliculitis, disseminate and recurrent

…developed Superficial perivascular infiltrate of lymphocytes Spongiosis in infundibula Correlation clinicopathologic Spongiosis in infundibula is responsible for the appearance of tiny infundibulocentric papules. Differential diagnosis histopatholog…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…cytes along the dermoepidermal junction and in the epidermis, spongiosis, ballooning, pallor across viable epidermis, and scale-crusts = Mucha-Habermann disease, acute  All the changes pictured have occurred beneath the original normal cornified laye…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ully developed  This lesion, formed fully, displays prominent spongiosis, an exaggeration of a finding invariable in all lesions very early in the course of the disease. In brief, lymphocytes precede neutrophils in the epidermis of an incipient lesio…

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