Search Results for: spongiosis

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Therapeutic Strategies in Dermatology

Bullous Pemphigoid: Key Points

…nts as urticarial plaques and tense bullae, with eosinophilic spongiosis, edema, and subepidermal blister formation on biopsy. Bullous pemphigoid often requires systemic immunosuppression to adequately control the disease, usually with corticosteroid…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ary in the basal layer in foci, and in association with scant spongiosis in the spinous zone = Mycosis fungoides, patch  The diagnosis of mycosis fungoides can be made from findings in the epidermis alone, as shown here. Note the absence of any colle…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…filtrate of lymphocytes, edema of the papillary dermis, focal spongiosis and scale-crust, and variable number of extravasated erythrocytes = Gianotti-Crosti syndrome + Wedge-shaped infiltrate, strikingly atypical lymphocytes, and some lymphocytes oft…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…later as collarettes of scale, the latter being testimony to spongiosis having been present within the epidermis, the collarettes representing the residuum of a mound of parakeratosis that largely desquamated. A plaque of nummular dermatitis is give…

Histologic Diagnosis of Inflammatory Skin Diseases

Infundibulofolliculitis, disseminate and recurrent

…developed Superficial perivascular infiltrate of lymphocytes Spongiosis in infundibula Correlation clinicopathologic Spongiosis in infundibula is responsible for the appearance of tiny infundibulocentric papules. Differential diagnosis histopatholog…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…cytes along the dermoepidermal junction and in the epidermis, spongiosis, ballooning, pallor across viable epidermis, and scale-crusts = Mucha-Habermann disease, acute  All the changes pictured have occurred beneath the original normal cornified laye…

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