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A Clinical Atlas of 101 Common Skin Diseases

Melanoma

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A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule.

A Clinical Atlas of 101 Common Skin Diseases

Melanoma

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Therapeutic Strategies in Dermatology

Melanoma: Principles of Management of Melanoma

Principles of Management of Melanoma Prognosis is largely determined by histologic features of the primary melanoma (depth of invasion and/or the degree to which the tumor has invaded the skin, as well as ulceration and mitotic index). The major ind…

Therapeutic Strategies in Dermatology

Melanoma

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Therapeutic Strategies in Dermatology

Non-Melanoma Skin Cancers (NMSC): Basal Cell Carcinoma (BCC) and Squamous Cell Carcinoma (SCC): Non-Melanoma Skin Cancers (NMSC): Basal Cell Carcinoma (BCC) and Squamous Cell Carcinoma (SCC) – Initial Evaluation–Bowen’s Disease (Squamous Cell Carcinoma in Situ) – genprac

Initial Evaluation: Bowen’s Disease (Squamous Cell Carcinoma in Situ) The eponym BowenÂ’s disease is used to describe squamous cell carcinoma in situ on any cutaneous surface except the glans penis. It bears several clinical features: Untreate…

Therapeutic Strategies in Dermatology

Melanoma: Key Points

…25 per 100,000 persons, with approximately 70,000 new cases of melanoma and 8,650 melanoma-related deaths reported in 2009. New cases may arise de novo or from pre-existing pigmented skin lesions which evolve. The expansion in size, change in pigment…

Therapeutic Strategies in Dermatology

Melanoma: Treatment

…ation or other immunomodulatory drugs are ongoing in stage III melanoma patients. Chemotherapy and adjuvant radiotherapy might be proposed in certain cases and should be indicated in melanoma centers. Referral to a dermatologist with expertise in cut…

Therapeutic Strategies in Dermatology

Melanoma: Initial Evaluation

Initial Evaluation Clinical variants of melanoma: Superficial spreading melanoma (SSM): The most common form of melanoma, and typically presents with irregular borders, highly uneven pigmentation and/or unusual pigmentation (i.e., blue, pink, red,…

Therapeutic Strategies in Dermatology

Melanoma: References

…rences National Cancer Institute: http://www.cancer.gov (2009) Melanoma Treatment (PDQ). Dummer R et al (2008) Cutaneous malignant melanoma: ESMO clinical recommendations for diagnosis, treatment and follow-up, Ann Oncol, 19:ii86-88. Garbe C et al (2…

Therapeutic Strategies in Dermatology

Melanoma: Clinical Cases

…ed and does not identify any other suspicious lesions. Biopsy: melanoma, 0.7 mm thickness, Clark’s level II; no ulceration present, and mitotic index Follow-up The patient goes for wide local excision with 1 cm margins; there is no residual m…

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