Therapeutic Strategies in Dermatology

Photosensitivity Dermatoses: Overview

Photosensitive drug eruptions, polymorphous light eruption, chronic actinic dermatitis (CAD -includes the conditions previously called photosensitive eczema, actinic reticuloid and persistent light reaction). Photosensitivity dermatoses are caused e…

A Clinical Atlas of 101 Common Skin Diseases

Phototoxic Dermatitis

An inflammatory process that represents the combined effects of a toxic substance applied topically or administered systemically in combination with the effects of ultraviolet light, the result being a caricature of sunburn. The lesions consist of e…

A Clinical Atlas of 101 Common Skin Diseases

Lupus Erythematosus

An inflammatory process that expresses itself in the skin in protean ways that are variations on a basic pathologic theme, and includes evanescent patches on the face (“butterfly blush”), scaly papules and plaques that resolve with atrop…

Histologic Diagnosis of Inflammatory Skin Diseases

Burns

Burns Synonyms Thermal injuries Presentation stereotypical Age and sex Any age and both sexes Distribution of lesions Regions that usually are exposed rather than covered Configuration of lesions Depends on the particular type of burn; bizarre shape…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vesicular Dermatitis

See Fig. 5.239 A-C. Figure 5.239 A-C. Patterns of vesiculation: intraepidermal, subepidermal, and intra- and subepidermal. “Blister” and “vesiculobullous” are terms generic for lesions of the skin that usually are elevated…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Apoptosis?

“… this distinctive type of necrosis (apoptosis)…has previously been called shrinkage necrosis on morphological grounds.” Kerr JFR. Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide ranging implicatio…