Therapeutic Strategies in Dermatology

Photosensitivity Dermatoses: Overview

…Eruptions Photosensitive drug eruptions may present either as sunburn (a phototoxic response) or photoallergy (an eczematous response). Photoallergic eruptions may be either eczematous or lichenoid histologically. It may be impossible to clearly defi…

A Clinical Atlas of 101 Common Skin Diseases

Phototoxic Dermatitis

…d systemically in combination with the effects of ultraviolet light, the result being a caricature of sunburn. The lesions consist of erythema and blisters, some of which may be large bullae, and occur on sites exposed directly to ultraviolet light….

A Clinical Atlas of 101 Common Skin Diseases

Lupus Erythematosus

An inflammatory process that expresses itself in the skin in protean ways that are variations on a basic pathologic theme, and includes evanescent patches on the face (“butterfly blush”), scaly papules and plaques that resolve with atrop…

Histologic Diagnosis of Inflammatory Skin Diseases


…hysical, or electromagnetic. Phototoxic eruption is akin to a sunburn that is exaggerated. Differential diagnosis clinical Irritant contact dermatitis can be differentiated only by assistance of history clinical. Findings histopathologic for burns Ea…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…perivascular infiltrate of lymphocytes = Any burn, including sunburn/phototoxic dermatitis     Broad Zone of Parakeratosis Containing Neutrophils Neutrophils, or remnants of them (nuclear “dust”), disposed mostly as s…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…rocytes in the dermis, and a reddish patch of a blush or of a sunburn from erythrocytes congested within dilated blood vessels of the superficial plexus. PHLEGMON [Gk. phlegma (flame, inflammation)]: Cellulitis brought into being usually by microaero…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vesicular Dermatitis

…ation are expected in burns inflicted in different ways, from sunburn to frostbite, a distinctive example of which results from application of electrodesiccation in the course of dermatologic surgical procedures (Fig. 5.305 A&B). The nuclei of ce…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology


…h as Civatte bodies, colloid bodies, single-cell necrobiosis, sunburn cells, and dyskeratotic cells without their basic nature having been recognized… Weedon D, Searle J, Kerr JF. Apoptosis: its nature and implications for dermatopathology. Am…