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A Clinical Atlas of 101 Common Skin Diseases

Syphilis

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An inflammatory process, caused by the spirochete Treponema pallidum, that tends to evolve through three stages, namely, primary (typified usually by a solitary chancre), secondary (characterized by widespread macules and papules on skin and mucous membranes in conjunction with signs and symptoms of systemic disease), and tertiary (manifested by gummas in the skin and destructive lesions also in the bones, eyes, brain, and elsewhere, resulting in debilitation and often death).

A Clinical Atlas of 101 Common Skin Diseases

Syphilis

An inflammatory process, caused by the spirochete Treponema pallidum, that tends to evolve through three stages, namely, primary (typified usually by a solitary chancre), secondary (characterized by widespread macules and papules on skin and mucous…

Therapeutic Strategies in Dermatology

Syphilis (Lues)

An inflammatory process, caused by the spirochete Treponema pallidum, that tends to evolve through three stages, namely, primary (typified usually by a solitary chancre), secondary (characterized by widespread macules and papules on skin and mucous…

Therapeutic Strategies in Dermatology

Syphilis (Lues): Overview

Overview The treatment of syphilis is based on the duration of infection and the organ systems involved. Five groups can be distinguished: primary, secondary, or early syphilis of less than 1 year’s duration; infection of indeterminate length,…

Therapeutic Strategies in Dermatology

Syphilis (Lues): Key Points

Key Points The treatment of syphilis is based on the duration of infection and the organ systems involved. Five subtypes of syphilis can be distinguished: primary, secondary, or early syphilis of less than 1 year’s duration; infection of inde…

Therapeutic Strategies in Dermatology

Syphilis (Lues): Treatment

Treatment First-line therapy: The first-line therapy for syphilis depends on the duration of infection and the immune competence of the host. Patients’ contacts should be traced and evaluated for possible syphilis infection. All documented cases of…

Therapeutic Strategies in Dermatology

Syphilis (Lues): Initial Evaluation

Initial Evaluation Clinical atlas images: Primary syphilis: Secondary syphilis: Tertiary syphilis: Congenital syphilis: Differential diagnosis Differential diagnosis of primary syphilis Herpes simp…

Therapeutic Strategies in Dermatology

Balanitis: Overview

Overview Balanitis is a nonspecific term meaning inflammation of the glans penis. It is most commonly multifactorial in etiology, restricted to the uncircumcised, and presents as a mildly symptomatic scaly, red macule or patch. Acute suppurative bal…

Therapeutic Strategies in Dermatology

Viral Exanthems: Initial Evaluation

Initial Evaluation Patients with a viral exanthem often present with a non-specific morbilliform eruption. In some cases, the skin disease as part of a constellation of other symptoms may indicate a specific viral etiology. Measles German m…

Therapeutic Strategies in Dermatology

Syphilis (Lues): References

…genital Read PJ and Donovan B (2012) Clinical aspects of adult syphilis, Int Med Journal, 42: 614-619. Mattei, PL et al (2012) Syphilis: an emerging infection, AFP, 86: 433-440. Roett MA, Mayor MT, Uduhiri KA (2012) Diagnosis and management of genita…

Therapeutic Strategies in Dermatology

Syphilis (Lues): Clinical Cases

Clinical Case Case 1 21-year-old male who has sex with men Past medical history notable for HIV infection; he is currently not taking antiretroviral medications and his CD4+ count is 43 Review of systems is notable only for recent fevers in asso…

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