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Therapeutic Strategies in Dermatology

Lupus: Key Points

…disease that presents across a broad spectrum of cutaneous and systemic manifestations. It may be cutaneous-only or systemic with cutaneous manifestations; some patients with systemic lupus do not have cutaneous involvement. Diagnostic evaluation of…

Therapeutic Strategies in Dermatology

Psoriasis: Principles of Psoriasis Management

…e diagnosis is not clear Joint involvement Psoriasis requiring systemic immunosuppression, biologic therapy, or phototherapy Localized psoriasis of the scalp, hands, feet, or nails (which often require systemic immunosuppression in the setting of sev…

Therapeutic Strategies in Dermatology

Urticaria Pigmentosa/ Mastocytosis: Overview

…most common presentation. Adults have the potential to develop systemic lesions, although most have indolent systemic mastocytosis which has a benign natural history. Therapy is determined by the symptoms caused by the mast cell proliferation, and th…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Treatment

…on and optimizing wound care. Inflammatory control may require systemic immunosuppression and/or the use of multiple therapeutic agents in combination. First steps Systemic corticosteroids are the initial treatment of choice for patients with establ…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…. Localized aggressive disease and generalized disease require systemic chemotherapy. For debilitating extensive cutaneous disease, symptomatic visceral involvement, and relapses after radiation therapy, systemic chemotherapy with single agents such…

Therapeutic Strategies in Dermatology

Acne Vulgaris: Treatment

…+/- scarring) First-line therapy: topical retinoid + systemic antibiotic + benzoyl peroxide Combine a systemic antibiotic with a topical retinoid such as tretinoin cream (0.025%-0.05% for the face, 0.1% for the trunk) or gel (0.01 % for th…

Therapeutic Strategies in Dermatology

Borreliosis (Lyme Disease): Key Points

…gic testing is essential for diagnosis, especially in cases of systemic involvement. Avoidance of tick bites is the primary prevention of Lyme disease. Many late complications of Lyme disease may be prevented by systemic antibiotic therapy early in t…

Therapeutic Strategies in Dermatology

Bullous Pemphigoid: Overview

…e agents may be used in patients who do not rapidly respond to systemic steroids or in patients in whom the use of systemic steroids is contraindicated. If the patient has complications or side effects from the prednisone, has persistent severe dise…

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