Histologic Diagnosis of Inflammatory Skin Diseases

Epidermis

…ure 1.19 Cytoplasm of a spinous cell filled nearly entirely by tonofibrils, except for a small number of mitochondria and scattered ribosomes. Tonofibrils surround the nucleus and radiate toward the periphery, where they converge on desmosomes. (x950…

Histologic Diagnosis of Inflammatory Skin Diseases

Melanocytes

Melanocytes synthesize melanin. From precursors in the neural crest, melanocytes migrate normally to the epidermis, the bulb of hair follicles, epithelia of various mucous membranes, leptomeninges, inner ear, and a few other tissues (Fig. 1.61). Pri…