Histologic Diagnosis of Inflammatory Skin Diseases

Epidermis

…re 1.19 Cytoplasm of a spinous cell filled nearly entirely by tonofibrils, except for a small number of mitochondria and scattered ribosomes. Tonofibrils surround the nucleus and radiate toward the periphery, where they converge on desmosomes. (x9500…

Histologic Diagnosis of Inflammatory Skin Diseases

Melanocytes

…ytes. Figure 1.65 A melanocyte contains melanosomes but no tonofibrils. (x17,000) (Courtesy of Ken Hashimoto, M.D.) Figure 1.66 In a melanocyte, spherical and elliptical membrane-bound melanosomes are present at various stages of development. (…