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A Clinical Atlas of 101 Common Skin Diseases

Dermatofibrosarcoma Protuberans

A malignant nonepithelial neoplasm (a sarcoma) presumably of perineural fibrocytes that presents itself usually on the trunk, but sometimes elsewhere, such as the extremities, face, and scalp. A papule of it tends to become a plaque, a nodule, a tum…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…es are recognized by criteria morphologic: (1) Langhans” giant cells, seen commonly in tuberculoid granulomas and characterized by a horseshoe-shaped rim of nuclei at the outermost part of abundant eosinophilic cytoplasm; (2) Touton giant cells

Therapeutic Strategies in Dermatology

Herpes Simplex: Clinical Cases

…anck smear of blister fluid reveals presence of multinucleated giant cells Viral DFA and culture for HSV obtained Acyclovir 400 mg p.o. t.i.d. x 5 days Follow-up in 1 week Follow-up visit Lesions resolving HSV DFA is positive and viral culture reve…

A Clinical Atlas of 101 Common Skin Diseases

Xanthogranuloma

A granulomatous inflammatory process that presents itself in children as multiple yellowish papules or nodules that often are associated with systemic involvement of eyes, liver, and testes. In adults it is usually a solitary lesion confined to the…

A Clinical Atlas of 101 Common Skin Diseases

Neurofibromatosis

A constellation of lesions that represent disorders of melanocytes (e.g., axillary "freckles" and café au lait "spots") and of proliferations of Schwann cells (e.g., papules, nodules, and tumors of neurofibroma). The cutaneous lesions may be accompanied by neoplasms with neural differentiation that are situated in nerves (e.g., acoustic neuroma) and in the brain (e.g., gliomas), […]

Therapeutic Strategies in Dermatology

Folliculitis (including pseudofolliculitis barbae): Key Points

Key Points Folliculitis is a term that encompasses follicular-based inflamed papules or pustules that may stem from a wide variety of causes. Important causes of folliculitis include infection (bacterial, yeast, and viral), friction, medication-in…

A Clinical Atlas of 101 Common Skin Diseases

Melanocytic Nevi and Melanotic Macules

Hamartomas (“congenital” melanocytic nevi) and benign neoplasms (“acquired” melanocytic nevi) of various specific types, all of which are composed of abnormal melanocytes and manifested clinically as lesions of different colo…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Benign and Malignant Cells?

…. Rather than trying to kll the highly dysplastic or malignant cells directly, a benign cell booster increases the fitness of the more benign cells, which may be either normal or benign clones, so that they may outcompete more advanced or malignant c…

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