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A Clinical Atlas of 101 Common Skin Diseases

Arthropod Assaults

Papules, nodules, vesicles, and sometimes bullae that develop in response to “bites” of arthropods, among the most common offenders being mosquitoes, bedbugs, and mites of scabies….

A Clinical Atlas of 101 Common Skin Diseases

Herpes Simplex, Zoster, and Varicella

…ains of herpesvirus and typified when fully developed by tense vesicles, herpes simplex consisting of grouped vesicles on an erythematous base, zoster being made up of vesicles, sometimes hemorrhagic ones, that course along a dermatome of an adult us…

A Clinical Atlas of 101 Common Skin Diseases

Scabies

An inflammatory process caused by the acarus Sarcoptes scabiei and consisting of papules, papulovesicles, papulopustules, and vesicles, some arranged in linear or curvilinear tracks (burrows). Sometimes nodules are present, especially in the interdi…

A Clinical Atlas of 101 Common Skin Diseases

Bullous Pemphigoid and Herpes Gestationis

An inflammatory disease of older people; signs include widespread erythematous macules and patches, urticarial papules and plaques, and vesicles and bullae, the blisters often arising on urticarial plaques. Sometimes lesions are localized, e.g., to…

A Clinical Atlas of 101 Common Skin Diseases

Fixed Drug Eruption

Circular orange-red-blue macule(s) or patch(es) that often becomes a papule(s) or plaque(s) and vesiculates, healing with hyperpigmentation, and that occurs repeatedly at the very same cutaneous and/or mucous membrane site(s), especially the genital…

A Clinical Atlas of 101 Common Skin Diseases

Pemphigus Foliaceus

A blistering inflammatory disease in which acantholysis occurs in the upper part of the spinous zone or granular zone of the epidermis, the result of the process being flaccid blisters that give way to erosions and crusts accompanied by erythema. Wh…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vesicular Dermatitis

…mixed (Fig. 5.243 A&B). Figure 5.240 A-C. Position of a vesicle within an epidermis: suprabasal, intraspinous, and “subcorneal.” Figure 5.241 A-C. Mechanism of formation of a vesicle: spongiosis, ballooning, and acantholysis….

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

…stributed randomly Individual lesions Papules, papulovesicles, vesicles, and, at times, bullae; crusts form consequent to resolution of vesicles and/or the effects of excoriation Course Usually resolve without treatment in a matter of a few weeks Var…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…esponse to an insect “bite” A tense intraepidermal vesicle above a wedge-shaped, superficial and deep perivascular and interstitial infiltrate is diagnostic of a “bite” by an insect. The vesicle often is positioned directly ab…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

…. Figure 5.318 A&B. Transformation of an intraepidermal vesicle into a pustule: Necrosis of keratocytes is chemotactic for neutrophils. What now is an intraepidermal pustule began as an intraepidermal vesicle brought into being by herpesvirus,…

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