Clinical Case Studies

Xanthelasma

…in resurfacing are the favored modalities for the treatment of xanthelasma. Laser skin resurfacing was thought to be the best choice in this case because it would remove the xanthelasma and at the same time improve the dark circles and crinkling of t…

A Clinical Atlas of 101 Common Skin Diseases

Xanthomas, Including Xanthogranulomas

Deposits of lipid in the skin and sometimes in subcutaneous tissues as a consequence often, but not always, of hyperlipidemia. The lipid deposits are expressed as yellowish papules and plaques, and nodules and tumors….

Histologic Diagnosis of Inflammatory Skin Diseases

Xanthomas

Xanthomas Presentation stereotypical Age and sex Adults of both sexes Distribution of lesions Localized or widespread Individual lesions Macules, papules, plaques, and nodules Course Some lesions, e.g., eruptive xanthomas, involuting when serum lipi…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Histiocytoses?

“The concept of grouping as related disorders those which feature proliferation of cytologically mature benign histiocytic elements in either localized or more widespread form will be elaborated.” Halprin KM, Lorincz AL. Disseminated x…

Differential Diagnosis in Dermatopathology

Granuloma annulare vs. Eruptive xanthoma

Deposits of lipid in the skin and sometimes in subcutaneous tissues as a consequence often, but not always, of hyperlipidemia. The lipid deposits are expressed as yellowish papules and plaques, and nodules and tumors….

Histologic Diagnosis of Inflammatory Skin Diseases

Deposits of lipid in the skin and sometimes in subcutaneous tissues as a consequence often, but not always, of hyperlipidemia. The lipid deposits are expressed as yellowish papules and plaques, and nodules and tumors….

Histologic Diagnosis of Inflammatory Skin Diseases

Dermatofibroma

Dermatofibroma Synonyms Benign fibrous histiocytoma Fibroma dura Subepidermal nodular sclerosis Histiocytoma Histiocytoma cutis Sclerosing hemangioma Fibroma simplex or fibroma durum Nodulus cutaneus Fibrome en Pastille Dermatofibroma lenticulare De…

Differential Diagnosis in Dermatopathology

Discussions

Both granuloma annulare and eruptive xanthoma consist of foci of histiocytes positioned mostly in the upper part of the dermis, sometimes in palisaded array and sometimes as solitary units splayed between bundles of collagen. Moreover, both conditio…