A Clinical Atlas of 101 Common Skin Diseases

Herpes Simplex, Zoster, and Varicella

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Conditions caused by infection with different strains of herpesvirus and typified when fully developed by tense vesicles, herpes simplex consisting of grouped vesicles on an erythematous base, zoster being made up of vesicles, sometimes hemorrhagic ones, that course along a dermatome of an adult usually, and varicella being characterized by widespread discrete vesicles in children as a rule.

A Clinical Atlas of 101 Common Skin Diseases

Herpes Simplex, Zoster, and Varicella

Conditions caused by infection with different strains of herpesvirus and typified when fully developed by tense vesicles, herpes simplex consisting of grouped vesicles on an erythematous base, zoster being made up of vesicles, sometimes hemorrhagic…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella

Conditions caused by infection with different strains of herpesvirus and typified when fully developed by tense vesicles, herpes simplex consisting of grouped vesicles on an erythematous base, zoster being made up of vesicles, sometimes hemorrhagic…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Key Points

…y Points Primary varicella infection (chickenpox) and herpes zoster are both caused by varicella zoster virus (VZV). Herpes zoster (shingles) represents activation of varicella zoster virus from cranial or dorsal root ganglion, thus affecting the s…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Treatment

Treatment Herpes zoster First-line therapy: The first-line therapy for herpes zoster includes the treatment of the acute eruption and therapy for herpetic neuralgia and post-herpetic neuralgia. Confirmation of herpes zoster by viral direct fluoresc…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: References

References Bruxelle J, Pinchinat S (2012) Effectiveness of antiviral treatment on acute phase of herpes zoster and development of post herpetic neuralgia: review of international publications, Med et Mal infectieuses (English), 42:53-58. Chen N, Li…

Therapeutic Strategies in Dermatology

Herpes Simplex: Initial Evaluation

Initial Evaluation Herpes simplex may result in painful or burning crusted grouped vesicles near the mouth or nares, often recurrent in the same location. Grouped (herpetiform) pustular lesions resulting in erosions with scalloped borders are sugges…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Initial Evaluation

Initial Evaluation Herpes zoster (shingles) Note that vesicles and papulovesicular lesions are grouped with an erythematous to hemorrhagic base. Primary varicella infection Differential diagnosis Herpes simplex virus (o…

Therapeutic Strategies in Dermatology

Bullous Pemphigoid: Overview

Overview Bullous pemphigoid is usually a self-limited inflammatory subepidermal blistering disorder of the elderly, in which circulating auto antibodies to epitopes in the basement membrane zone bind to this region and initiate a cascade of inflamma…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Clinical Cases

Clinical Cases Case 1 68-year-old healthy male No significant past medical history (normal renal function) Review of systems is noncontributory History of primary varicella infection as child No sick contacts Presents for management of 3 days…