Chapter 1. Acanthosis Nigricans


Pigmented plaques formed by confluence of smooth-surfaced soft papules, some of which may become polypoid, traversed by accentuations of skin folds. This disease has a predilection for intertriginous regions. The condition may develop consequent to obesity, an endocrine disorder, or a malignant neoplasm in an internal organ. Morphologically, i.e., clinically and histopathologically, the appearance of the altered skin is the same, irrespective of cause.

at001g00a.jpg at001g00b.jpg at001g00c.jpg