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Chapter 1. Acanthosis Nigricans

Distribution

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Fig. 1-1

Widespread acanthosis nigricans. This implies concurrence of an internal malignancy.


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Fig. 1-2

Confluent papillomatosis of the lips and buccal mucosa.


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Fig. 1-3

Bilateral involvement of the axillae in this obese young man with an endocrine disorder.


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Fig. 1-4

The neck is a favorite site.


Individual Lesions

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Fig. 1-5

Closely set tiny papules in linear array.


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Fig. 1-6

Lesions situated over joints. Note how dark are the fingers in contrast to the rest of the skin.


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Fig. 1-7

Pigmented plaque with mammillated surface.


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Fig. 1-8

Pigmented, slightly elevated plaque with a gently papillated smooth surface, in this instance punctuated by atrophic striae.


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Fig. 1-9

Polypoid excrescences, as well as subtle papules. Grooves that traverse plaques represent accentuation of skin lines.


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Fig. 1-10

Ill-defined plaque, thrown into folds, made up of prominent, smooth-surfaced papules, some of them polypoid.


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Fig. 1-11

Pigmented plaque in which skin folds are accentuated.


New! Additional Images

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Fig. 1-12

Acanthosis nigricans: Brown papules, some of which have become confluent to form a plaque, are intersected by lines normal for skin. The dark brown macule is a Clark’s nevus.