Clinical Reference / Clinical Atlas / Squamous Cell Carcinoma

Squamous Cell Carcinoma


A malignant neoplasm of keratinocytes that when present as a keratotic macule or papule on skin damaged badly by sunlight is referred to as solar keratosis. When present as a plaque it is termed Bowen’s disease, and when present as many papules in the anogenital region it is called bowenoid papulosis. Solar keratosis, Bowen’s disease, and bowenoid papulosis, as well as arsenical keratosis and radiation keratosis, are euphemisms for various types of superficial squamous cell carcinoma. Very episodically, neoplastic cells of those types of squamous cell carcinoma proliferate wildly, and the primary neoplasm then consists of aggregations that extend throughout the dermis and well into the subcutaneous fat, from which sites they rarely may metastasize.