1991 Lavker, Cotsarelis, Wei, Sun

 
Stem cells of pelage, vibrissae and eyelash follicles: the hair cycle and tumor formation. Ann NY Acad Sci. 1991;642:214—25.
 

Message

 
Bulge stem cells in mouse follicles may be pluripotential, i.e., responsible not only for development of the follicle, but for sebaceous glands and epidermis, too.
 

Critique

 
Sebaceous units, i.e., lobules and ducts, derive from mantle epithelium that emanates from the junction of infundibulum and isthmus at some distance from "the bulge."
 
Epidermal epithelium is reconstituted after loss of it from epithelial cells contributed by the upper portion of follicles, i.e., infundibula and eccrine ducts. Eccrine ducts and infundibula are unassociated with bulges.