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< Current issue
Dermatopathology: Practical & Conceptual January - March 1996
>
Searching for Diogenes: Uncloaking the Mantle
Martin Sangueza, MD
Michael Anthony Radonich, MD
A. Bernard Ackerman, MD
Introduction
1876 Unna P
1889 Kölliker A
1895 Benda C
1897 Pinkus F
1902 Hertwig O
1927 Pinkus F
1935 Zimmermann KW
1956 Epstein W, Kligman AM
1963 Strauss JS, Pochi PE
1964 Madsen A
1971 Pinkus H
1972 Hegedus SL, Schorr WF
1976 Pinkus H and Mehregan AH
1987 Ishikawa K
1990 Leshin B, White WL
1991 Mehregan A, Hashimoto K
1992 Jakubovic H, Ackerman AB
1992 Montagna W, Kligman AM, Carlisle KS
1993 Narisawa Y, Hashimoto K, Kobda H
1993 Ackerman AB, deViragh P, and Chongchitnant N
1993 Steffen C
1994 Steffen C, Ackerman AB
1995 Mehregan AH, Hashimoto K, Mehregan DA, Mehregan DR
1995 deViragh PA
1996 Ackerman AB (
Fig. 19
)
SEE ALSO
-
mantle
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1976 Pinkus H and Mehregan AH
A Guide to Dermatohistopathology, 2nd ed. New York: Appleton-Century-Crofts, 1976 (
Fig. 11
).
View Figure
Fig. 11 (orig. Fig. 188). Alopecia areata. A. Some relatively normal hair follicles and a "miniature follicle" often found in alopecia areata. This follicle also has the configuration of a "cloaked hair" due to sebaceous atrophy. This not too uncommon abnormality has no pathologic significance in itself (Epstein and Kligman, 1956). H&E, 75X. B. Inflammatory infiltrate associated with follicles of reduced size containing remnants of inner root sheath, but no hairs. H&E, 135X.
Message
A not uncommon malformation of vellus follicles on a face results from replacement of the sebaceous gland by a sheet of basal cells that surrounds the middle portion of the hair root like a skirt or cloak (the mantle of Felix Pinkus). It can be seen in histologic sections as epithelial spurs that flank the isthmus.
Critique
The mantle is a normal follicular structure that early in life and much later in life represents what remains of sebaceous glands that have involuted. At puberty, in contrast, the mantle is the anlage of sebaceous glands. At no stage is the mantle a malformation that replaces sebaceous glands.
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