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< Current issue
Dermatopathology: Practical & Conceptual July - September 2001
>
Evolution in Thinking: Criteria for Clinical Diagnosis of Melanoma, 1947–2000: A Critique in Historical Perspective
Mary Aldrene L. Tan, M.D.
A. Bernard Ackerman, M.D.
Introduction
Becker and Obermayer
Ormsby and Montgomery
Lever
Sulzberger and Wolf
Pillsbury, Shelley, and Kligman
Fitzpatrick and Clark
Lewis and Wheeler
Wayte
Domonkos
Sanderson
Borrie
Clark
Sneddon
Meara
Fry
Sauer
Callen, Stawiski, and Voorhees
Roenigk
Ackerman
McGovern
Roses, Harris, and Ackerman
Dobson and Abele
Ackerman
Ackerman
Friedman, Rigel, and Kopf
Fitzpatrick, Rhodes, Sober, and Mihm
Koh and Rogers
McCarthy et al.
Habif
MacKie
Marks
Mooi WJ and Krausy
Fitzpatrick, Milton, Balch, Shaw, McCarthy, and Sober
National Institutes of Health Consensus Conference
Levine
Holzle, Kind, Plewig, and Burgdorf
Moynihan
Epstein
Marghoob, Slade, Kopf, Rigel, and Friedman
Arndt, Wintroub, Robinson, and LeBoit
Elder and Elenitsas
Barnhill
Maize et al.
Langley, Fitzpatrick, and Sober
Sagebiel
Farmer and Hood
Fleischer, Feldman, Katz, and Clayton
Ackerman, Kerl, Sánchez, et al.
References
SEE ALSO
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melanoma
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Marks
"Table 3.2 Danger signs of melanoma
Increase in size of pre-existing mole or development of new pigmented lesion
Irregular outline developing in pre-existing mole or presence of this feature in new pigmented lesion
Irregular degree of pigmentation (variegation) in pre-existing mole or this feature in new pigmented lesion
Irritation, soreness, inflammation, crusting, erosion, bleeding in pre-existing mole or in new pigmented lesion"
Marks R.
Sun-damaged Skin.
United Kingdom: Martin Dunitz Ltd., 1992:55.
Brief critique
Two of the four "dangerous signs of melanoma," according to Marks, are dependent on history provided by a patient rather than on morphologic observation by a physician, namely, "increase in size" and "irritation, soreness, inflammation . . ." of a pigmented lesion. The crucial findings for identification of melanoma by a patient should be no different than those utilized by a physician. Those signs, by definition, must be morphologic, rather than anecdotal. Terms like "irregular outline" and "irregular degree of pigmentation" are vague and imprecise. By the time that there is "crusting, erosion, bleeding" of a melanoma, the prognosis is markedly unfavorable; metastases probably have occurred.
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