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Dermatopathology: Practical & Conceptual July - September 2002
Contrary View: The Breast is not an Organ
but a Distinctive Region of Skin and Subcutaneous Tissue: Part I, Embryologic Development
A. Bernard Ackerman, M.D.
Galen Kessler, M.D.
Tibor Gyorfi, M.D.
The Breast is Not a Sweat Gland
Development of Skin and Subcutaneous Fat
Development of the Folliculosebaceous-Apocrine Unit
Development of the Eccrine (Sweat) Unit
Development of the Breast, Including Folliculosebaceous-Apocrine Units and Eccrine Units of It
The Breast in Literature
"The origin of the breast is thought to be related to that of the sweat glands and integument." Mitchell GW. Bassett LW.
The Female Breast and Its Disorders,
"The breast is a modified sweat gland covered by skin and subcutaneous tissue." Rosai J.
Ackerman's Surgical Pathology,
"The breast is a modified skin sweat gland that develops into a complex functional structure in the female, but remains as a rudimentary organ in the male." Cotran RS, Kumar V, Robbins SL.
Robbins Pathologic Basis of Disease,
"Mammary glands are modified sweat glands with the specialized function of providing nutrients for the newborn infant." Tavassoli F,
Pathology of the Breast,
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