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Dermatopathology: Practical & Conceptual April - June 2003
>
Erratum: Proliferating Tricholemmal Cystic Carcinoma (Revision of Chapter XXV of the Volume Titled
Neoplasms with Follicular Differentiation,
2nd edition by Ackerman, Reddy, and Soyer, Ardor Scribendi, Ltd., 2001)
A. Bernard Ackerman M.D.
Joan Mones, D.O.
Abstract
Editor’s Note
Historical Perspective
Features Clinically
Findings Histopathologically
Stereotypical Example of a Proliferating Tricholemmal Cystic Acanthoma
Stereotypical Examples of Proliferating Tricholemmal Cystic Carcinomas
Cytopathologic Attributes of Proliferating Tricholemmal Cystic Carcinoma
Origin of Proliferating Tricholemmal Cystic Carcinoma
Differentiation of Proliferating Tricholemmal Cystic Carcinoma
Problems in Diagnosis of Proliferating Tricholemmal Cystic Carcinoma
Histopathologic Differential Diagnosis
Biologic Behavior
Suppositions about Pathogenesis
Conclusion
Acknowledgements
References
SEE ALSO
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proliferating tricholemmal cystic carcinoma
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Cytopathologic Attributes of Proliferating Tricholemmal Cystic Carcinoma
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Fig. 8AC
Proliferating tricholemmal cystic carcinoma.
The cells that make up this distinctive type of carcinoma, especially the ones situated at the periphery of aggregations, have nuclei that are crowded, large, and pleomorphic; many are in mitosis. The cytoplasm is abundant and brightly eosinophilic (in sections stained by hematoxylin and eosin) as a consequence of abnormal cornification reminiscent of that at the isthmus of a normal follicle.
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